| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
We estimated the nicotine metabolism from the values of nicotine and trans-3’-hydroxycotinine among patients who started the smoking cessation treatment. The difference of the urinary cotinine levels between the measures at the beginning of the treatment and 2 weeks after the treatment was evaluated. The interaction term between the level of nicotine metabolism and time was calculated for the analysis. The cotinine level was largely decreased 2 weeks after the treatment, regardless the level of nicotine metabolism. The interaction effects between oxidative stress levels and time were implied, although they were not statistically significant.
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