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Study of abnormal social behavior in patients with brain injury.

Research Project

Project/Area Number 26461766
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Psychiatric science
Research InstitutionKyoto University

Principal Investigator

Keita Ueda  京都大学, 医学研究科, 助教 (60573079)

Co-Investigator(Kenkyū-buntansha) 杉原 玄一  京都大学, 医学研究科, 特定病院助教 (70402261)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords高次脳機能障害 / 社会的行動障害 / 外傷性脳損傷 / び漫性軸索損傷 / 社会行動障害 / 神経画像 / 神経心理学 / 脳損傷
Outline of Final Research Achievements

Not only the volume of Corpus Callosum, but also the value of fractional anisotropy was found to be decreased in patients with diffuse axonal injury. And the value of fractional anisotropy was correlated with the score of processing speed. As to the social function of patients with brain injury, the relationship was found between the ability to infer the emotion of others with the score of social function, especially that of cognitive independence assessed by The Craig Handicap Assessment and Reporting Technique. In addition, volume reduction in brain stem was found to be related with the severity score which was made by the Glasgow Coma Scale and the duration of post traumatic amnesia.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (12 results)

All 2017 2016 2015 2014

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Acknowledgement Compliant: 4 results,  Open Access: 2 results) Presentation (6 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results) Book (1 results)

  • [Journal Article] Facial emotion recognition in patients with focal and diffuse axonal injury.2017

    • Author(s)
      Yassin W, Callahan BL, Ubukata S, Sugihara G, Murai T, Ueda K.
    • Journal Title

      Brain Injury

      Volume: 28 Issue: 5 Pages: 1-7

    • DOI

      10.1080/02699052.2017.1285052

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Disturbance of time orientation, attention, and verbal memory in amnesic patients with confabulation2016

    • Author(s)
      Shingaki H., Park P., Ueda K., Murai T., Tsukiura T.
    • Journal Title

      Journal of Clinical and Experimental Neuropsychology

      Volume: 38 Issue: 2 Pages: 171-182

    • DOI

      10.1080/13803395.2015.1094027

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Corpus Callosum Pathology as a Potential Surrogate Marker of Cognitive Impairment in Diffuse Axonal Injury.2015

    • Author(s)
      Ubukata S, Ueda K, Sugihara G, Yassin W, Aso T, Fukuyama H, Murai T.
    • Journal Title

      J Neuropsychiatry Clin Neurosci.

      Volume: 28 Issue: 2 Pages: 97-103

    • DOI

      10.1176/appi.neuropsych.15070159

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Hypothalamic-Amygdalar-Brainstem Volume Reduction in a Patient with Narcolepsy Secondary to Diffuse Axonal Injury.2015

    • Author(s)
      Yassin W, Sugihara G, Oishi N, Kubota M, Ubukata S, Murai T, Ueda K.
    • Journal Title

      Journal of Clinical Sleep Medicine

      Volume: Feb. 10.

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Social cognition and its relationship to functional outcomes in patients with sustained acquired brain injury.2014

    • Author(s)
      Shiho Ubukata, Rumi Tanemura, Miho Yoshizumi, Genichi Sugihara, Toshiya Murai, and Keita Ueda.
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: 10 Pages: 2061-2068

    • DOI

      10.2147/ndt.s68156

    • NAID

      120005517899

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 社会的行動障害の精神医学的側面2016

    • Author(s)
      上田敬太
    • Organizer
      日本高次脳機能障害学会第40回学術総会
    • Place of Presentation
      長野県松本市
    • Year and Date
      2016-11-11
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Neural basis of cognitive impairments in patients with diffuse axonal injury2015

    • Author(s)
      Ubukata S., Ueda K., Sugihara G., Yasshin, W., Aso T., Fukuyama H., and Murai T.
    • Organizer
      Organization for Human Brain Mapping 2015
    • Place of Presentation
      ホノルル(ハワイ)
    • Year and Date
      2015-06-15
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] びまん性軸索損傷患者における脳構造変化および認知機能障害の神経基盤に関する研究2014

    • Author(s)
      生方志浦、上田敬太、杉原源一、Walid Yassin、麻生俊彦、福山秀直、村井俊哉
    • Organizer
      包括脳シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-12-12
    • Related Report
      2014 Research-status Report
  • [Presentation] 精神科医から診た高次脳機能障害2014

    • Author(s)
      上田敬太
    • Organizer
      「高次脳機能障害者の社会参加支援の推進に関する研究」東北ブロックシンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2014-11-30
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 頭部外傷の社会行動障害2014

    • Author(s)
      上田敬太
    • Organizer
      高次脳機能障害学会
    • Place of Presentation
      仙台
    • Year and Date
      2014-11-29
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Neural basis of cognitive impairments in patients with diffuse axonal injury2014

    • Author(s)
      Ubukata S, Keita U, Genichi S, Yassin W, Sasaki H, Aso T, Fukuyama H and Murai T.
    • Organizer
      新学術国際シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-07-05
    • Related Report
      2014 Research-status Report
  • [Book] 高次脳機能障害の考え方と画像診断 アパシー2016

    • Author(s)
      武田克彦 村井俊哉 編著
    • Total Pages
      306
    • Publisher
      中外医学社
    • Related Report
      2016 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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