| Project/Area Number |
26462116
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Cardiovascular surgery
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
Osamu Sakai 京都府立医科大学, 医学(系)研究科(研究院), 助教 (10298432)
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| Co-Investigator(Kenkyū-buntansha) |
渡辺 太治 京都府立医科大学, 医学(系)研究科(研究院), 特任助教 (20448723)
神田 圭一 京都府立医科大学, 医学(系)研究科(研究院), 講師 (60295649)
中山 泰秀 国立研究開発法人国立循環器病研究センター, その他, 研究員 (50250262)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 生体内組織形成術 / カバードステント / ステントグラフト / 大口径血管 / 生体内組織形成 |
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| Outline of Final Research Achievements |
We tried experiments to apply Biocovered stent, which was prepared for medium and small caliber vessels and performed a transplant experiment, to large-diameter vessels. For large diameter vessels, self-expanding stents are mainstream not the balloon expandable stent, so Gianturco Z - stent which is a tracheal stent and 20 mm diameter silicone tube were used. As a result of trial and error, without removing Biotube produced subcutaneously, Z-stent was deployed in the lumen, and the silicone tube was inserted again into it. After 4 weeks, it was removed, and Biocovered stent for large diameter integrated Z-stent covered with autologous tissue membrane was able to be obtained.
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