| Project/Area Number |
26462327
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Anesthesiology
|
|---|
| Research Institution | Hirosaki University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
廣田 和美 弘前大学, 医学研究科, 教授 (20238413)
丹羽 英智 弘前大学, 医学部附属病院, 講師 (20374845)
|
|---|
| Project Period (FY) |
2014-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
|---|
| Keywords | 全身麻酔 / 睡眠 / 内因性覚醒物質 / オレキシン / ノルアドレナリン / MCH / 鎮痛 / 麻酔時間 / 麻酔 / ERAS |
|---|
| Outline of Final Research Achievements |
Recent social situation, aging society, required shortening of hospital stay, reduction of medical expense although aged patients always have potential risk for developing unpredicted complication at peri-operative period that would consume medical resources and expense. In consideration to this state of affairs, it should be expected that anesthesiology provide safety, amenity, and economic efficiency more and more. This research intended to find a basic perception for patient care based on the request mentioned above with relation to sleep science.
An endogenous wake-promoting substance, orexin, plays crucial role in general anesthesia including anesthesia duration, post anesthetic sleep disturbance, and analgesia interacting with central noradrenergic neuronal activity.
|
