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Randomized controlled trial on prevention of root caries and arrest of early stage root caries

Research Project

Project/Area Number 26462888
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Conservative dentistry
Research InstitutionNagasaki University

Principal Investigator

KUBO Shisei  長崎大学, 病院(歯学系), 准教授 (80145268)

Co-Investigator(Kenkyū-buntansha) 木村 泰男  長崎大学, 医歯薬学総合研究科(歯学系), 助教 (30253686)
林田 秀明  長崎大学, 病院(歯学系), 講師 (20238140)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords根面う蝕 / 予防 / 進行抑制 / ランダム化比較試験 / フッ化物 / 歯磨剤 / フッ素
Outline of Final Research Achievements

Volunteers had to have at least 1 exposed root labial (buccal) or lingual (palatal) surface in the mouth. Subjects were randomly assigned to two arms of the study: fluoride contained and non-fluoride toothpastes. Questionnaires were used to collect data on general health, oral hygiene, diet, smoking and alcohol habits. Caries risk was determined based on the number of restorations or caries during the last 3 years, oral hygiene status and the results of salivary test, such as flow rate, pH, buffering ability and levels of cariogenic bacteria. After recording exposed dentin surfaces and taking pictures of them, subjects were recalled every 3 months for a regular checkup. The effect of fluoride in the tooth paste on the prevention of root caries is still unclear since no root caries has not been found in both groups due to the short-term follow-up of 3 months.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (4 results)

All 2016 2015

All Journal Article (2 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (1 results) (of which Invited: 1 results) Book (1 results)

  • [Journal Article] Root caries management: Evidence and consensus based report2016

    • Author(s)
      Yasuko Momoi, Akihiko Shimizu, Mikako Hayashi, Satoshi Imazato, Masako Unemori, Yuichi Kitasako, Shisei Kubo, Rena Takahashi, Syozi Nakashima, Toru Nikaido, Masayoshi Fukushima, Morioki Fujitani, Chinami Yamaki, Kenichi Sugai
    • Journal Title

      Cariology in Current Oral Health Reports

      Volume: 3 Issue: 2 Pages: 117-123

    • DOI

      10.1007/s40496-016-0084-0

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] なぜ、根面う蝕こそメインテナンスが大事なの?2016

    • Author(s)
      久保至誠
    • Journal Title

      歯科衛生士

      Volume: 40 Pages: 22-33

    • Related Report
      2016 Annual Research Report
  • [Presentation] 根面う蝕に関する現状と今後の課題2016

    • Author(s)
      久保至誠
    • Organizer
      日本オーラルヘルス歯科学会
    • Place of Presentation
      東京八重洲ホール(東京都・中央区)
    • Year and Date
      2016-03-13
    • Related Report
      2015 Research-status Report
    • Invited
  • [Book] 日本歯科保存学会 編 う蝕治療ガイドライン 第2版2015

    • Author(s)
      桃井保子、清水明彦、林美加子、今里聡、畦森雅子、北迫勇一、久保至誠、高橋礼奈、中嶋省志、二階堂徹、福島正義、冨士谷盛興、八巻千波、菅井健一
    • Total Pages
      126
    • Publisher
      永末書店
    • Related Report
      2015 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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