Development of photofunctionalized zirconia implant
| Project/Area Number |
26462937
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Showa University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | インプラント / ジルコニア / 紫外線 / ナノジルコニア / UV |
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| Outline of Final Research Achievements |
We aimed to develop a zirconium (Ce-TZP) implant fixture functionalized by ultraviolet (UV). Ce-TZP/Al2O3 treated with hydrofluoric acid (HF) irradiated by UV with shifting the wavelength and the irradiation time. The adhesion, proliferation, differentiation, and expression of bone related genes of osteoblastic cell (MC3T3-E1) on these samples enhanced by 15-40% under the wavelength and time of a specific pattern. Similarly, osseointegration capability on UV functionalized Ce-TZP increased significantly compared to control group. Oxidant stress induced cell cytotoxicity by UV irradiation did not show deleterious effect on cellular level. We concluded about this matter that there is no our safety concern.
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Report
(4 results)
Research Products
(4 results)
