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Objective pathological diagnosis method of refractory temporomandibular disorders - Novel biomarker for central sensitization -

Research Project

Project/Area Number 26462955
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Prosthodontics/ Dental materials science and
Research InstitutionKeio University

Principal Investigator

Muraoka Wataru  慶應義塾大学, 医学部(信濃町), 講師(非常勤) (70317254)

Co-Investigator(Kenkyū-buntansha) 和嶋 浩一  慶應義塾大学, 医学部(信濃町), 講師(非常勤) (70138105)
Research Collaborator Usuda Syou  
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords口腔顔面痛 / 顎関節症 / 中枢性感作 / 残感覚 / 時間的加重 / 熱刺激
Outline of Final Research Achievements

In order to apply the thermal stimulation protocol in a clinical setting for distinguishing the central sensitization in temporomandibular disorders, small device was newly developed which can distinguish central sensitization on equal terms with a conventional large-sized thermal stimulators.
It showed that small device for diagnosing central sensitization, and large-sized device did not have a difference about intra-class reliability and inter-class reliability.By using small device for diagnosing central sensitization, it was suggested that central sensitization could distinguish easily in a chair side.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2017 2015

All Presentation (4 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Presentation] AACMD workshop Demonstration Lesson of Clinical Reasoning for Diagnosis of Orofacial Pain2017

    • Author(s)
      Wataru Muraoka
    • Organizer
      The 17th Asian Academy of Craniomandibular Disorders congress
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 歯科に適応のない薬剤をどうするか 口腔顎顔面領域の痛みと治療薬2017

    • Author(s)
      村岡 渡
    • Organizer
      第27回日本口腔内科学会/第30回日本口腔診断学会 学術大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] シンポジウム:歯科薬物療法の現状と課題~口腔の痛みに対する薬物治療~2017

    • Author(s)
      村岡 渡
    • Organizer
      第37回日本歯科薬物療法学会学術大会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 国際頭痛分類第3版beta版による三叉神経痛(典型的三叉神経痛と有痛性三叉神経ニューロパチー)の臨床統計的検討2017

    • Author(s)
      村岡渡、臼田頌、西須大徳、佐藤仁、柴崎竣一、吉武桃子、莇生田整治、河奈裕正、中川種昭、和嶋浩一
    • Organizer
      第22回一般社団法人日本口腔顔面痛学会
    • Related Report
      2017 Annual Research Report
  • [Patent(Industrial Property Rights)] 中枢感作診断装置及びその動作方法2015

    • Inventor(s)
      和嶋浩一、佐藤仁、西須大徳、村岡渡、中川種昭、加藤康憲
    • Industrial Property Rights Holder
      学校法人慶應義塾、ケージーエス株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-04-01
    • Related Report
      2015 Research-status Report
    • Overseas

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Published: 2014-04-04   Modified: 2019-03-29  

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