| Project/Area Number |
26506006
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
宇宙生命学
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| Research Institution | University of Yamanashi |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 繁殖生物 / 生殖細胞 / 初期発生 / 発生工学 / 宇宙生物学 / 受精胚凍結 / 胚培養装置 / 宇宙繁殖生物学 / 受精卵凍結 / 培養容器の開発 / 卵子凍結保存 / 繁殖生物学 / 受精 |
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| Outline of Final Research Achievements |
The main problem for mammalian reproduction experiments in space is the very small size of embryos (80-100 μm), which generally requires researchers to learn appropriate handling techniques. Presently, the thawing and culturing of embryos are difficult even on the ground, especially if the experimentalist has not had much practice. In addition, this project will be performed under μG conditions, which makes it difficult to predict how to handle the embryos. Therefore, it is not realistic to expect untrained astronauts to do this directly. For this reason, we have started to develop a very simple thawing and culture system of mouse embryos using commercially available products. Using this system, astronauts will not need to handle the embryos, and will not need prior training. To overcome the impracticality of handling and culturing mammalian embryos, we planned a simple embryo thawing and culture system, which will allow the astronauts to perform this project smoothly.
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