Genome epidemiological study on sleep and mental health
Project/Area Number |
26507006
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
睡眠科学
|
Research Institution | Shiga University of Medical Science |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
Yoshikawa Takeo 理化学研究所, 脳科学総合研究センター, チームリーダー (30249958)
Owada Yuji 東北大学, 大学院 医学系研究科, 教授 (20292211)
|
Research Collaborator |
Gerstner Jason R. Washington State University
Perron Isaac J. University of Pennsylvania
Riedy Samantha M. Washington State University
Van Dongen Hans P. A. Washington State University
Galante Raymond J. University of Pennsylvania
Dickinson Kaitlin University of Wisconsin-Madison
Yin Jerry C. P. University of Wisconsin-Madison
Pack Allan I. University of Pennsylvania
Frank Marcos G. Washington State University
|
Project Period (FY) |
2014-04-01 – 2018-03-31
|
Project Status |
Completed (Fiscal Year 2017)
|
Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2017: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 睡眠障害 / メンタルヘルス / ゲノム / 疫学 / 睡眠 / 不眠 / 国際共同研究 / うつ病 / 国際情報交換 |
Outline of Final Research Achievements |
The mammalian brain-type fatty acid binding protein (Fabp7) is expressed in astrocytes. We found from our genome epidemiological study that the missense mutation FABP7.T61M is associated with fragmented sleep. This phenotype was recapitulated in mice and fruit-flies bearing similar mutations. This was a result from an international collaborating study.
|
Report
(4 results)
Research Products
(97 results)
-
-
-
-
[Journal Article] Combined association of clinical and lifestyle factors with non-restorative sleep: The Nagahama Study.2017
Author(s)
Matsumoto T, Tabara Y, Murase K, Takahashi Y, Setoh K, Kawaguchi T, Muro S, Kadotani H, Kosugi S, Sekine A, Yamada R, Nakayama T, Mishima M, Matsuda F, Chin K.
-
Journal Title
PLoS One.
Volume: 12
Issue: 3
Pages: e0171849-e0171849
DOI
NAID
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
[Journal Article] Normal sleep requires the astrocyte brain-type fatty acid binding protein FABP72017
Author(s)
Gerstner JR, Perron IJ, Riedy SM, Yoshikawa T, Kadotani H, Y Owada, van Dongen HPA, Galante RJ, Dickinson K, Yin JCP, Pack AI, Frank MG
-
Journal Title
Science Advances
Volume: 3
Issue: 4
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
-
-
-
-
-
[Journal Article] Obstructive sleep apnea in preschool-aged Japanese children - efficiency of screening using lateral neck radiography.2016
Author(s)
Kitamura T, Miyazaki S, Kobayashi R, Kadotani H, Kanemura T, Komada I, Nishikawa M, Okawa M, Koizumi H, Takeuchi S, Suzuki H
-
Journal Title
Acta Otolaryngol.
Volume: 22
Issue: 6
Pages: 1-7
DOI
Related Report
Peer Reviewed
-
-
-
[Journal Article] Knee Pain and Low Back Pain Additively Disturb Sleep in the General Population: A Cross-Sectional Analysis of the Nagahama Study.2015
Author(s)
Murase K, Tabara Y, Ito H, Kobayashi M, Takahashi Y, Setoh K, Kawaguchi T, Muro S, Kadotani H, Kosugi S, Sekine A, Yamada R, Nakayama T, Mishima M, Matsuda S, Matsuda F, Chin K.
-
Journal Title
PLoS One
Volume: 10
Issue: 10
Pages: e0140058-e0140058
DOI
NAID
Related Report
Peer Reviewed / Open Access
-
-
-
-
[Journal Article] Work report by the task force of the Japanese Academy of Dental Sleep Medicine for clinical practice guidelines of oral appliances2015
Author(s)
Okuno K, Sato K, Arisaka T, Gotoh M, Sasao Y, Taga H, Hamada S, Hosohama K, Yamamoto T, Irie M, Kashiwazaki J, Kadoatni H, Sato M, Suzuki M, Higurashi N, Sakakibara H, Shimizu T, Sugisaki M, Tonogi M
-
Journal Title
Journal of Oral Sleep Medicine
Volume: 1
Pages: 148-153
Related Report
Peer Reviewed / Open Access
-
-
-
[Journal Article] Associations among chronic obstructive pulmonary disease and sleep disordered breathing in an urban male working population in Japan.2014
Author(s)
Azuma M, Chin K, Yoshimura C, Takegami M, Takahashi K, Sumi K, Nakamura T, Nakayama-Ashida Y, Minami I, Horita S, Oka Y, Oga T,Wakamura T, Fukuhara S, Mishima M, Kadotani H.
-
Journal Title
Respiration
Volume: 88
Issue: 3
Pages: 234-243
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
[Journal Article] Screening of Clock Gene Polymorphisms Demonstrates Association of a PER3 Polymorphism with Morningness-Eveningness Preference and Circadian Rhythm Sleep Disorder2014
Author(s)
Hida A, Kitamura S, Katayose Y, Kato M, Ono H, Kadotani H, Uchiyama M, Ebisawa T, Inoue Y, Kamei Y, Okawa M, Takahashi K, Mishima K
-
Journal Title
Scientific Reports
Volume: 4(6309)
Issue: 1
Pages: 1-6
DOI
NAID
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
[Journal Article] Gastroesophageal reflux disease symptoms and dietary behaviors are significant correlates of short sleep duration in the general population: The Nagahama Study.2014
Author(s)
Murase, K., Tabara, Y., Takahashi, Y., Muro, S., Yamada, R., Setoh, K., Kawaguchi, T., Kadotani, H., Kosugi, S., Sekine, A., Nakayama, T., Mishima, M., Chiba, T., Chin, K., Matsuda, F
-
Journal Title
Sleep
Volume: 37
Issue: 11
Pages: 1809-15
DOI
Related Report
Peer Reviewed / Open Access
-
[Journal Article] An association between anti-nuclear antibodies and HLA class II locus and heterogeneous characteristics of staining patterns: The Nagahama Study.2014
Author(s)
Terao C, Ohmura K, Yamada R, Kawaguchi T, Shimizu M, Tabara Y, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Matsuda F, Tsuneyo Mimori T on behalf of the Nagahama Study Group.
-
Journal Title
Arthritis Rheumatol.
Volume: 66
Issue: 3_suppl
Pages: 3395-403
DOI
Related Report
Peer Reviewed / Open Access
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 32015
Author(s)
角谷寛
Organizer
日本睡眠学会第40回定期学術集会開催
Place of Presentation
栃木県総合文化センター
Year and Date
2015-07-02 – 2015-07-03
Related Report
Invited
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] 認知症における認知機能の低下と呼吸関連睡眠障害の関連2014
Author(s)
山田尚登, 松尾雅博, 高橋正洋, 村上純一, 青木浄亮, 青木泰亮, 青木直亮, 水元洋貴, 並川綾子, 原宏子, 宮川正治, 角谷寛
Organizer
日本睡眠学会 第39回定期学術集会
Place of Presentation
あわぎんホール(徳山市)
Year and Date
2014-07-03 – 2014-07-04
Related Report
-
-
-
[Presentation] 睡眠ビッグデータ2014
Author(s)
角谷寛
Organizer
第53回日本生体医工学会大会
Place of Presentation
仙台国際センター
Year and Date
2014-06-24 – 2014-06-26
Related Report
Invited
-
-
-
-
-
-
-
-
-