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Development of quantitative analytical method for hexavalent chromium and trivalent chromium by detection of mammalian cellular pysiological changes

Research Project

Project/Area Number 26550084
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Environmental risk control and evaluation
Research InstitutionSuzuka National College of Technology

Principal Investigator

Ogawa Akiko  鈴鹿工業高等専門学校, その他部局等, 准教授 (90455139)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords六価クロム / 三価クロム / クロム検出 / 動物細胞 / 細胞機能 / クロム分析 / MTTアッセイ / LDH細胞毒性試験
Outline of Final Research Achievements

In this study, we developed analytical methods for hexavalent chromium and trivalent chromium separately using detection systems of mammalian cellular functional changes. The developed analytical method of trivalent is a new method to detect trivalent chromium directly and individually. The developed analytical method of hexavalent chromium can detect lower concentration than existing one. Additionally, these developed analytical methods can be applied for measuring chromium of iron and steel.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (9 results)

All 2017 2016 2015 2014

All Presentation (7 results) Book (2 results)

  • [Presentation] 細胞の代謝活性変化を利用したクロム検出2017

    • Author(s)
      小川亜希子, ウルジバートル サランゲア
    • Organizer
      化学工学会第82年会
    • Place of Presentation
      芝浦工業大学、東京
    • Year and Date
      2017-03-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] 動物細胞の機能変化を利用したクロム検出2016

    • Author(s)
      小川亜希子、保坂浩章、田中雄士
    • Organizer
      題68回日本生物工学会大会
    • Place of Presentation
      富山国際会議場、富山市
    • Year and Date
      2016-09-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] 動物細胞の生理機能変化を利用した6価クロムの検出2015

    • Author(s)
      保坂浩章、小川亜希子
    • Organizer
      第17回化学工学会学生発表会(徳島大会)
    • Place of Presentation
      徳島大学
    • Year and Date
      2015-03-07
    • Related Report
      2014 Research-status Report
  • [Presentation] 動物細胞の生理機能変化を利用した三価クロムの検出2015

    • Author(s)
      田中雄士、小川亜希子
    • Organizer
      第17回化学工学会学生発表会(徳島大会)
    • Place of Presentation
      徳島大学
    • Year and Date
      2015-03-07
    • Related Report
      2014 Research-status Report
  • [Presentation] 細胞膜の細胞膜上亜鉛トランスポーターの発現量比較と亜鉛による増殖抑制との関連2015

    • Author(s)
      岩田果久、小川亜希子
    • Organizer
      第17回化学工学会学生発表会(徳島大会)
    • Place of Presentation
      徳島大学
    • Year and Date
      2015-03-07
    • Related Report
      2014 Research-status Report
  • [Presentation] PANC-1とHep G2の亜鉛感受性とメタロチオネイン量との関連2015

    • Author(s)
      細川貴史、小川亜希子
    • Organizer
      第17回化学工学会学生発表会(徳島大会)
    • Place of Presentation
      徳島大学
    • Year and Date
      2015-03-07
    • Related Report
      2014 Research-status Report
  • [Presentation] 亜鉛による細胞増殖抑制と細胞の亜鉛取り込み能との関連2014

    • Author(s)
      小川亜希子、山田悠介、岩田果久
    • Organizer
      第66回日本生物工学会大会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2014-09-09 – 2014-09-11
    • Related Report
      2014 Research-status Report
  • [Book] Chapter 16 The application of mammalian cells for assessmentof metallic products (in vitro process)2016

    • Author(s)
      Akiko Ogawa (
    • Total Pages
      18
    • Publisher
      Springer Japan
    • Related Report
      2015 Research-status Report
  • [Book] Corrosion Control and Surface Finishing: Environmentally Friendly Approaches,, Chapter 17 The Application of a Mammalian Cell (In vitro process2015

    • Author(s)
      Akiko Ogawa (Editorial supervisors: Hideyuki Kanematsu, Dana Barry)
    • Total Pages
      400
    • Publisher
      Springer Japan
    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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