Personal flow cytometry by ultra-compact high-spatial-resolution line spectroscopic imaging
Project/Area Number |
26560214
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Biomedical engineering/Biomaterial science and engineering
|
Research Institution | Kagawa University |
Principal Investigator |
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
|
Keywords | 分光 / ハイパースペクトルカメラ / 高感度化 / 蛍光標識 / フーリエ分光 / 光圧力 / 光ピンセット / フローサイトメトリー / 空間的位相シフト法 / スナップショット / 細胞 / 手のひらサイズ / ラマン散乱 / フローサイトメトリ |
Outline of Final Research Achievements |
We proposed the snapshot-type Fourier spectroscopic imaging for smartphone. For spectroscopic components analysis, such as non-invasive blood glucose sensors, the diffuse reflection lights from internal human skins are very weak for conventional hyperspectral cameras, such as AOTF (Acousto-Optic Tunable Filter) type. For improving sensitivity of our spectroscopic imager, the wide-field-stop & beam-expansion method was proposed. We installed concave-cylindrical lens between the wider slit and objective lens as a beam expander. We successfully obtained the spectroscopic characters of hemoglobin from reflected lights from human fingers.
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Report
(4 results)
Research Products
(14 results)