| Project/Area Number |
26560383
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Applied health science
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
UEO-IIO Tomoe 岡山大学, 大学院保健学研究科, 助教 (80613158)
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| Co-Investigator(Renkei-kenkyūsha) |
KATAOKA Mikio 岡山大学, 大学院保健学研究科, 教授 (50177391)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | COPD / 精油 / 炎症 / アロマセラピー / ラベンダー精油 / 肺気腫 |
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| Outline of Final Research Achievements |
We examined the inflammatory effects of the essential oils used in aromatherapy with murine model of elastase induced chronic obstructive pulmonary disease (COPD). We exposed the COPD mice to lavender essential oil or eucalyptus essential oil by inhalation, and then measured pulmonary functions, total cell numbers in bronchoalveolar lavage fluids, histological analysis and mRNA expressions in lungs of mice. Lavender essential oil suppressed alveolar damage in COPD mice. Eucalyptus essential oil suppressed the infiltration of inflammatory cells into BALF and the alveolar damage in early phase of pathologic process of murine COPD. We found that lavender essential oil and eucalyptus essential oil had the anti-inflammatory effects in murine model of COPD.
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