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In vivo PET brain connection imaging

Research Project

Project/Area Number 26560471
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Brain biometrics
Research InstitutionNational Center of Neurology and Psychiatry

Principal Investigator

Ichinohe Noritaka  国立研究開発法人国立精神・神経医療研究センター, 神経研究所 微細構造研究部, 部長 (00250598)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords生体内繊維連絡 / PET / コレラトキシン・ベータsubunit / リガンド
Outline of Final Research Achievements

We have attached PET visible ligand with anterograde- and retrograde tracer, cholera-toxin-beta-subunit (CTB). This methods will be important to simultaneous recording from areas directly connected, and align diffusion tensor imaging with real connection. We have examined how far CTB moved during four hours. We found that CTB could move contralateral cortical areas. We have developed to bind CTB and ligand. We have tested various condition for this methods. For example, we have injected PET tracers on other's intention, and found not only prefrontal surface areas, but also cingulate cortex. Both are related to sympathy and empathy. We will plan to simultaneous recording from these two areas for examining computational style from recognition to sympathy.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2015 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 4 results,  Acknowledgement Compliant: 2 results) Remarks (1 results)

  • [Journal Article] Mirror neurons in a New World monkey, common marmoset2015

    • Author(s)
      Suzuki W, Banno T, Miyakawa N, Abe H, Goda N, Ichinohe N
    • Journal Title

      Frontiers in Neuroscience 9 459

      Volume: 9 Pages: 459-459

    • DOI

      10.3389/fnins.2015.00459

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Functional columns in superior temporal sulcus areas of the common marmoset.2015

    • Author(s)
      Suzuki W, Tani T, Banno T, Miyakawa N, Abe H, Ichinohe N
    • Journal Title

      Neuroreport

      Volume: 26 Issue: 18 Pages: 1133-1139

    • DOI

      10.1097/wnr.0000000000000483

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Anatomical inputs to sulcal portions of areas 9m and 8Bm in the macaque monkey.2015

    • Author(s)
      Eradath MK, Abe H, Matsumoto M, Matsumoto K, Tanaka K, Ichinohe N.
    • Journal Title

      Front Neuroanat

      Volume: 9 Pages: 30-30

    • DOI

      10.3389/fnana.2015.00030

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 2. On-going elucidation of mechanisms of primate specific synaptic spine development using the common marmoset (Callithrix jacchus).2015

    • Author(s)
      Ichinohe N.
    • Journal Title

      Neurosci Res

      Volume: 93 Pages: 176-178

    • DOI

      10.1016/j.neures.2014.10.019

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Remarks] http://www.ncnp.go.jp/nin/guide/r_mic/index.html

    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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