Synthesis of Escherichia coli Trap using Protein Microtube
Project/Area Number |
26600030
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Multi-year Fund |
Research Field |
Nanomaterials chemistry
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Research Institution | Chuo University |
Principal Investigator |
|
Co-Investigator(Renkei-kenkyūsha) |
AKIYAMA Motofusa 中央大学, 理工学部, 助教 (90467697)
|
Project Period (FY) |
2014-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
Keywords | ナノ材料 / 蛋白質 / マイクロチューブ / 大腸菌 / 電子顕微鏡 / アルブミン / 交互積層法 |
Outline of Final Research Achievements |
Microorganism is efficiently captured into the one-dimensional pore-space interior of protein microtube. We synthesized cylindrical hollow structure composed of human serum albumin by layer-by-layer assembly technique using microporous polycarbonate membrane, and revealed that Escherichia coli (E. coli K12) is encapsulated into the microtubes (outer diameter : 1 μm). This microtube“E. coli trap”might be applicable to eliminate enterohemorrhagic E. coli O157.
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Report
(3 results)
Research Products
(21 results)