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A numerical study of functional dyspepsia

Research Project

Project/Area Number 26600151
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Computational science
Research InstitutionTohoku University

Principal Investigator

Imai Yohsuke  東北大学, 工学(系)研究科(研究院), 特任准教授 (60431524)

Research Collaborator MIYAGAWA Taimei  東北大学, 大学院医工学研究科, 博士後期課程学生
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords胃 / 食物流動 / 数値流体力学 / 消化器系 / バイオメカニクス / 撹拌 / 計算力学 / 蠕動運動 / 数値シミュレーション / 消化器 / 計算バイオメカニクス
Outline of Final Research Achievements

To understand the relationship between the peristaltic contraction and the flow in the stomach, we have developed a numerical model of gastric flow. This model is based on a multi-phase flow modeling, an anatomically realistic geometry of the stomach, and a parametric model of peristaltic contractions. Antral recirculation is generated in the stomach. Our result shows that when peristaltic wave velocity increases, the strength of antral recirculation increases, resulting in enhancement of gastric mixing. We also show that mixing strength per one contraction becomes lower when the initiation period of peristaltic contractions is shorter.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2015 2014 Other

All Int'l Joint Research (2 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Int'l Joint Research] University of Auckland(New Zealand)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] National University of Singapore(Singapore)

    • Related Report
      2015 Annual Research Report
  • [Presentation] Clarification of Relationship between Gastric Mixing and Movement of Wall2015

    • Author(s)
      T. Miyagawa, Y. Imai, S. Ishida, T. Yamaguchi, T. Ishikawa
    • Organizer
      The 8th Asian-Pacific Conference on Biomechanics
    • Place of Presentation
      Sapporo, Japan
    • Year and Date
      2015-09-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Modeling of flow in the stomach2014

    • Author(s)
      Y. Imai, I. Kobayashi, T. Miyagawa, S. Ishida, T. Ishikawa, T. Yamaguchi
    • Organizer
      4th Japan-Switzerland Workshop on Biomechanics
    • Place of Presentation
      Shima Kanko Hotel, Mie, Japan
    • Year and Date
      2014-09-02
    • Related Report
      2014 Research-status Report
  • [Presentation] A numerical method for simulating gastric flow2014

    • Author(s)
      T. Miyagawa, Y. Imai, T. Yamaguchi, T. Ishikawa
    • Organizer
      11th World Congress on Computational Mechanics
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2014-07-25
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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