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A model for analyzing phenomena in multicellular organisms with multivariable polynomials -- Polynomial life --

Research Project

Project/Area Number 26610041
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Foundations of mathematics/Applied mathematics
Research InstitutionKyushu University

Principal Investigator

YOSHIDA Hiroshi  九州大学, 数理学研究院, 准教授 (60401262)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords多変数多項式 / 動的恒常維持 / 崩壊 / Polynomial life / 多細胞 / 単項簡約 / 多項式生命
Outline of Final Research Achievements

I proposed polynomial-life model towards analysis of some phenomena in multicellular organisms. Polynomial-life is multicells that are expressed as multivariable-polynomials, in which a cell is expressed as a term of polynomial. Starting with a single term and following reductions by set of polynomials, I simulate development from a cell to a multicell. In this framework I present various patterns through the polynomial-life model and discuss patterns maintained through turnover. Cell elimination seems to play an important role in turnover, which may shed some light on cancer or regenerative medicine.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (8 results)

All 2016 2015 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (7 results) (of which Int'l Joint Research: 2 results)

  • [Journal Article] A model towards analysis of regenerating patterns using multivariable polynomials ― Polynomial Life ―2016

    • Author(s)
      Hiroshi Yoshida
    • Journal Title

      21st International Symposium on Artificial Life and Robotics

      Volume: 21 Pages: 759-762

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] model for analyzing phenomena in multicellular organisms with multivariable polynomials2016

    • Author(s)
      吉田寛
    • Organizer
      第54回生物物理学会
    • Place of Presentation
      筑波
    • Related Report
      2016 Annual Research Report
  • [Presentation] A model for analyzing phenomena in multicellular organisms with multivariable polynomials2016

    • Author(s)
      Hiroshi Yoshida
    • Organizer
      EMBO Conference: From Functional Genomics to Systems Biology
    • Place of Presentation
      ハイデルベルク
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Polynomial-life model towards analysis of turnover and regeneration2015

    • Author(s)
      吉田 寛
    • Organizer
      第53回生物物理学会
    • Place of Presentation
      金沢大学
    • Year and Date
      2015-09-14
    • Related Report
      2015 Research-status Report
  • [Presentation] A model towards multicell-turnover patterns using multivariable polynomials ― Polynomial Life ―2015

    • Author(s)
      Hiroshi Yoshida
    • Organizer
      Hybrid Systems Biology 2015
    • Place of Presentation
      Madrid, Spain
    • Year and Date
      2015-09-04
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] A model of multicellular organisms using multivariable polynomials ― Polynomial Life ―2015

    • Author(s)
      吉田 寛
    • Organizer
      数理生物学会
    • Place of Presentation
      同志社大学
    • Year and Date
      2015-08-27
    • Related Report
      2015 Research-status Report
  • [Presentation] Toward analysis of multicell-turnover patterns by using multivariable polynomials2014

    • Author(s)
      吉田 寛
    • Organizer
      第52回 生物物理学会
    • Place of Presentation
      札幌
    • Year and Date
      2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] Analysis of multicell-turnover patterns with multivariable polynomial modeling2014

    • Author(s)
      Hiroshi Yoshida
    • Organizer
      International Conference on Systems Biology
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2014-09-15 – 2014-09-17
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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