| Project/Area Number |
26620049
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Inorganic chemistry
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| Research Institution | Kyushu University |
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Principal Investigator |
Ohba Masaaki 九州大学, 理学(系)研究科(研究院), 教授 (00284480)
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| Co-Investigator(Renkei-kenkyūsha) |
KOSHIYAMA TOMOMI 九州大学, 大学院理学研究院, 助教 (30467279)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 金属錯体 / 脂質 / 膜チャネル / 膜ドメイン |
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| Outline of Final Research Achievements |
Creation of multifunctional reaction systems like photosynthesis in nature is one of the most considerable topics in current chemistry. Although various chemical reactors consisting of polymers and proteins have been studied, it is still difficult to construct reaction systems in which different functions work simultaneously. Here we focus on liposome, which is an artificially-prepared spherical vesicle composed of a bilayer of phospholipids, as a platform for linking functions. We succeeded in developing new synthetic methods, (1) the direct synthesis of coordination polymers in the inner aqueous phase through membrane channels and (2) the hierarchical integration of functional metal complexes using membrane domain structure.These composites of liposome and functional compounds exhibited well-linked and more effective functions successfully .
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