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Knowing how differences on the conditions of the water molecules in the tissues between a necrotic and the surround normal.

Research Project

Project/Area Number 26640090
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Tumor diagnostics
Research InstitutionUniversity of Fukui

Principal Investigator

MIYOSI NORIO  福井大学, 医学部, 助教 (40209961)

Project Period (FY) 2014-04-01 – 2015-03-31
Project Status Completed (Fiscal Year 2014)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2014: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywords核磁気共鳴診断画像 / 赤外分光病態形態学診断 / 癌組織内水分子状態 / 腫瘍壊死部 / 水分子 / 水素結合 / スピン横緩和 / MRI / FT-IR / 遠赤外領域 / 赤外分光
Outline of Final Research Achievements

Next 3 experiments has been cleared the water molecules condition in necrotic part was (1) presented more large amounts of the longer hydrogen bonding, (2) the longer lifetime components in T2-MR Imaging of horizontal Spin-Spin dielectric relaxation and (3) the relationship of the pink color in H & E staining were presented in necrotic area analyzed by Fractal theory.

Report

(2 results)
  • 2014 Annual Research Report   Final Research Report ( PDF )
  • Research Products

    (8 results)

All 2015 2014 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results,  Acknowledgement Compliant: 1 results) Presentation (3 results) (of which Invited: 3 results) Book (1 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] PD and PDT with porphyrin precurssors (5-ALA) in Japan.2014

    • Author(s)
      N. Miyoshi, Y. Fukunaga, S. Kaneko, H. Hisazumi
    • Journal Title

      J. Japan Soc. Laser Sur. & Med.

      Volume: 29 Pages: 164-168

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effect of gallium-porphyrin analogue ATX-70 on nitroxide formation from a cyclic secondary amine by ultrasound on the mechanism of sonodynamic activation.2014

    • Author(s)
      N. Miyoshi, V. Misik, and P. Riesz
    • Journal Title

      Radiation Research

      Volume: 143 Pages: 194-202

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] (特別講演) 5-Aminolevulinic Acid (5-ALA)と共に20年2015

    • Author(s)
      三好憲雄
    • Organizer
      第5回ポルフィリン-ALA学会
    • Place of Presentation
      早稲田大学・理工学部
    • Year and Date
      2015-04-25 – 2015-04-26
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] テラヘルツ波の癌特有のターゲットとして水分子となるだろうか?-癌生組織の分光計測から見た展望-2014

    • Author(s)
      三好憲雄
    • Organizer
      第5回テラテクビジネスセミナー(THz-biz 2013)-テラヘルツ波バイオセンシングの進展と展望-
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-10-18
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] (Plenary Lecture-10) Combination therapy and new nano-drug development for PDT2014

    • Author(s)
      N. Miyoshi
    • Organizer
      The 14th World Congress for International Photodynamic Association
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2014-05-29 – 2014-06-01
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Book] In hope of going over the present Clinical PD and PDT2014

    • Author(s)
      N. Miyoshi and R. H. Poittier (Editor)
    • Publisher
      三恵社
    • Related Report
      2014 Annual Research Report
  • [Remarks] 環太平洋化学会議2015

    • URL

      http://ala.umin.jp

    • Related Report
      2014 Annual Research Report
  • [Patent(Industrial Property Rights)] 重粒子線治療用増感剤、及びそれを用いた重粒子線治療法2014

    • Inventor(s)
      三好憲雄
    • Industrial Property Rights Holder
      三好憲雄
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-11-18
    • Related Report
      2014 Annual Research Report

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Published: 2014-04-04   Modified: 2016-06-03  

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