| Project/Area Number |
26660248
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Integrative animal science
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| Research Institution | Tokyo University of Agriculture and Technology |
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Principal Investigator |
Nagaoka Kentaro 東京農工大学, (連合)農学研究科(研究院), 准教授 (60376564)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | アミノ酸 / 記憶と学習 / ミルク / アミノ酸代謝 / 脳機能 / 母乳 / アミノ酸代謝酵素 |
|---|
| Outline of Final Research Achievements |
Amino acid which is the source of life, has been working as a variety of biologically active substances in the body . In this study, we confirmed that the expression of LAO, one of amino acid metabolite enzyme, in the hippocampus where is responsible for learning and memory . In addition, when comparing mice do not have LAO (LAO KO) and normal mice, LAO KO mice showed weak learning and memory activity. In the future, by examining in detail the amino acids that LAO to control , we may find the factors that increase the brain function .
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