New analysis of the avian inbreeding depression phenomenon using a technique of chimera production
| Project/Area Number |
26660262
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Integrative animal science
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| Research Institution | National Institute for Environmental Studies |
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Principal Investigator |
Kawashima Takaharu 国立研究開発法人国立環境研究所, 生物・生態系環境研究センター, 主任研究員 (90360362)
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| Research Collaborator |
Nagino Koki 早稲田大学, 大学院・先進理工学研究科・生命理工学専攻
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 近交退化 / キメラ / ウズラ / 鳥類 |
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| Outline of Final Research Achievements |
In this study, we attempted to propose a new experimental system for analyzing disorders caused by inbreeding by using Japanese quail as a model organism, in which the inbreeding depression phenomenon appears conspicuously. Strong inbreeding to the long-term closed colony of Japanese quails (NIES-L strain) resulted in delayed embryonic development and decreased hatching rate. In addition, the number of aggressive behaviors of males of NIES-L quail was significantly lower than that of other strains. We succeeded in visualizing the contribution of biologically labeled inbred quail cells to embryos by producing inbred-hybrid blastoderm chimeras. In the future, it is expected to investigate the causes of embryonic death and embryonic development abnormality by inbreeding.
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Report
(4 results)
Research Products
(3 results)
