| Project/Area Number |
26660262
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Integrative animal science
|
|---|
| Research Institution | National Institute for Environmental Studies |
|---|
Principal Investigator |
Kawashima Takaharu 国立研究開発法人国立環境研究所, 生物・生態系環境研究センター, 主任研究員 (90360362)
|
|---|
| Research Collaborator |
Nagino Koki 早稲田大学, 大学院・先進理工学研究科・生命理工学専攻
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
|---|
| Keywords | 近交退化 / キメラ / ウズラ / 鳥類 |
|---|
| Outline of Final Research Achievements |
In this study, we attempted to propose a new experimental system for analyzing disorders caused by inbreeding by using Japanese quail as a model organism, in which the inbreeding depression phenomenon appears conspicuously. Strong inbreeding to the long-term closed colony of Japanese quails (NIES-L strain) resulted in delayed embryonic development and decreased hatching rate. In addition, the number of aggressive behaviors of males of NIES-L quail was significantly lower than that of other strains. We succeeded in visualizing the contribution of biologically labeled inbred quail cells to embryos by producing inbred-hybrid blastoderm chimeras. In the future, it is expected to investigate the causes of embryonic death and embryonic development abnormality by inbreeding.
|
