| Project/Area Number |
26670069
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Environmental and hygienic pharmacy
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| Research Institution | Tokushima Bunri University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
HIMENO Seiichiro 徳島文理大学, 薬学部, 教授 (20181117)
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| Research Collaborator |
TOHMORI Chidzuru
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | ヒ素化学形態 / 無機ヒ素 / 有機ヒ素 / 淡水魚 / ヒ素汚染地域 / モノメチルアルソン酸 / ジメチルアルシン酸 / アルセノベタイン / カンボジア / メコン川 / ヒ素スペシエーション / 尿中ヒ素 / 未知ヒ素化合物 |
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| Outline of Final Research Achievements |
Arsenic poisoning of ground water is prevalent in Asian countries including Cambodia. The chemical forms of arsenic contained in ground water are inorganic arsenate (As(V)) and arsenite (As(III)). In addition to tube-well water, the sources of arsenic exposure include fish. In Cambodia, about 80% of the protein source for people is fish, mainly freshwater fish in the river. A little information is available on the chemical forms of arsenicals in freshwater fish. To properly evaluate arsenic exposure levels among Cambodian people, it is necessary to clarify the concentrations and chemical forms of arsenicals in freshwater fish.
Some types of freshwater fish contributed to the intakes of DMA, TMAO, and As(V). Further studies are required to precisely estimate the exposure levels of non-toxic and toxic forms of arsenicals among Cambodian people who are deeply dependent on freshwater fish consumption.
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