| Project/Area Number |
26670086
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General anatomy (including histology/embryology)
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
Terada Sumio 東京医科歯科大学, 大学院医歯学総合研究科, 教授 (00262022)
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| Co-Investigator(Kenkyū-buntansha) |
川岸 将彦 東京医科歯科大学, 大学院医歯学総合研究科, 助教 (60323606)
齊藤 健太 東京医科歯科大学, 大学院医歯学総合研究科, 助教 (60374659)
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| Co-Investigator(Renkei-kenkyūsha) |
TANII Takashi 早稲田大学, 理工学術院, 教授 (20339708)
KONDO Takao 名古屋大学, 理学研究科, 教授 (10124223)
JIN Takashi 理化学研究所, 生命システム研究センター, チームリーダー (80206367)
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| Research Collaborator |
TANI Tomomi 米国ウッズホール海洋生物学研究所, 研究員
KINJO Masataka 北海道大学, 先端生命, 教授
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Keywords | 顕微鏡技術 / 生体分子間相互作用ネットワーク / 蛍光相関分光法 |
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| Outline of Final Research Achievements |
As rotational properties sensitively reflect molecular interactions and intracellular environment, polarization-dependent fluorescence correlation spectroscopy can be a promising method to analyse various cell biological events. We constructed both new polarization-dependent fluorescence correlation spectroscopy and an analysis program for this purpose. In addition, we could develop new methods to label proteins of interests for our analysis.
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