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Risk factor analyses of medical-related death based on the postmortem medical investigations

Research Project

Project/Area Number 26670348
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical and hospital managemen
Research InstitutionUniversity of Fukui

Principal Investigator

INAI KUNIHIRO  福井大学, 医学部, 講師 (30313745)

Co-Investigator(Kenkyū-buntansha) NORIKI SAKON  福井大学, 医学部, 准教授 (30228374)
Co-Investigator(Renkei-kenkyūsha) KIMURA HIROHIKO  福井大学, 医学部, 教授 (10242596)
IHAYA AKIO  福井大学, 医学部, 名誉教授 (70142841)
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywordsリスクマネージメント / 病理解剖 / オートプシー・イメージング / 医療関連死 / 環境調査 / 死因
Outline of Final Research Achievements

Few studies are analyzed about the medical-related death (MRD) focused on the processes of human death. We explored the intermediate causes of death (InCD) associated with MRD. In the 38 InCD of natural death-related factors, 13 of the InCD were identified as potent MRD. Regarding the effectiveness of postmortem CT as an alternative method for the determination of the immediate cause of death (ImCD) in hospitalized patients, an autopsy-based prospective study was performed. The ImCD was correctly diagnosed in 74% of the subjects using postmortem CT, which was significantly higher than the accuracy of clinical diagnosis. Additionally, we performed the environmental assessment of CT inspection room during postmortem imaging. The airborne microbes and the foul-smell levels were significantly higher in the forensic bodies that in the medical autopsies. These basic data will be utilized to establish the guidelines and safety manuals for preventing MRD and postmortem CT imaging.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (23 results)

All 2016 2015 2014

All Journal Article (11 results) (of which Peer Reviewed: 7 results,  Open Access: 4 results,  Acknowledgement Compliant: 5 results) Presentation (11 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results) Book (1 results)

  • [Journal Article] Postmortem CT is more accurate than clinical diagnosis for identifying the immediate cause of death in hospitalized patients: a prospective autopsy-based study2016

    • Author(s)
      K.Inai, S.Noriki, K.Kinoshita, T.Sakai, H.Kimura, A.Nishijima, H.Iwasaki, H.Naiki
    • Journal Title

      Virchows Archiv

      Volume: 印刷中 Issue: 1 Pages: 101-109

    • DOI

      10.1007/s00428-016-1937-6

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Utility of postmortem imaging system for anatomical education in skull base surgery.2015

    • Author(s)
      Kodera T, Arishima H, Kitai R, Kikuta K, Iino S, Noriki S, Naiki H.
    • Journal Title

      Neurosurg Rev.

      Volume: 38 Issue: 1 Pages: 165-170

    • DOI

      10.1007/s10143-014-0574-2

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 肝下面から右臀部まで腹腔内外に腫瘍様浸潤をきたした放線菌症の1例2015

    • Author(s)
      宮永克也, 多保孝典, 林 秀樹, 千葉幸夫, 稲井邦博, 内木宏延
    • Journal Title

      日本臨床外科学会雑誌

      Volume: 76 Pages: 2582-2586

    • NAID

      130005149547

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ai画像と解剖を活用した教育プログラムについて2015

    • Author(s)
      西島昭彦, 法木左近, 稲井邦博, 飯野 哲, 木村浩彦
    • Journal Title

      Innervision

      Volume: 31 Pages: 56-59

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Aiから死後画像学への展望2015

    • Author(s)
      稲井邦博, 法木左近, 島田一郎, 木村浩彦, 西島昭彦, 木戸尚治, 内木宏延
    • Journal Title

      Innervision

      Volume: 30 Pages: 47-50

    • Related Report
      2015 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] 病理解剖からの新たな知見2015

    • Author(s)
      法木左近、木下一之
    • Journal Title

      Innervision

      Volume: 30 Pages: 44-46

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Aiから死後画像学への展開2015

    • Author(s)
      稲井邦博, 法木左近, 島田一郎, 木村浩彦, 西島昭彦, 木戸尚治, 内木宏延
    • Journal Title

      Innervision

      Volume: 30 Pages: 47-50

    • Related Report
      2014 Research-status Report
    • Acknowledgement Compliant
  • [Journal Article] イディオタイプ蛋白/尿酸ナトリウム結晶複合体ワクチンによる多発性骨髄腫に対する特異的免疫療法の検討(臨床第I相試験)2014

    • Author(s)
      酒巻一平, 大槻希美, 稲井邦博, 上田孝典, 津谷 寛
    • Journal Title

      GOUT AND NUCLEIC ACID METABOLISM

      Volume: 38 Issue: 1 Pages: 85-86

    • DOI

      10.6032/gnam.38.85

    • NAID

      130004680250

    • ISSN
      1344-9796, 2186-6368
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] オートプシー・イメージングの現在と未来(2)Aiの実際2014

    • Author(s)
      稲井邦博, 法木左近, 西島昭彦
    • Journal Title

      Medical Imaging Technology

      Volume: 32 Pages: 302-306

    • NAID

      130004691595

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Feasibility of liver weight estimation by postmortem computed tomography images: An autopsy study.2014

    • Author(s)
      Inai. K
    • Journal Title

      Pathology International

      Volume: 64 Issue: 7 Pages: 315-324

    • DOI

      10.1111/pin.12174

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Risk factor analysis for bone marrow histiocytic hyperplasia with hemophagocytosis: an autopsy study.2014

    • Author(s)
      Inai K, Noriki S, Iwasaki H.
    • Journal Title

      Virchows Arch

      Volume: 465 Issue: 1 Pages: 109-118

    • DOI

      10.1007/s00428-014-1592-8

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Clinical Applications of Multidisciplinary Computational Anatomy to Diagnosis - Progress Overview FY2015 -2016

    • Author(s)
      S.Kido, N.Hashimoto, Y.Hirano, H.Kim, H.Kimura, S.Noriki, K.Inai, H.Shouno
    • Organizer
      The 2nd International Symposium on the Project "Multidisciplinary Computational Anatomy"
    • Place of Presentation
      Nagoya, University of Nagoya
    • Year and Date
      2016-02-11
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 介在死因に着目した医療関連死の背景分析2015

    • Author(s)
      稲井邦博, 法木左近, 岩崎博道, 井隼彰, 夫内木宏延
    • Organizer
      第10回医療の質・安全学会学術集会
    • Place of Presentation
      千葉市, 幕張メッセ国際会議場
    • Year and Date
      2015-11-21
    • Related Report
      2015 Annual Research Report
  • [Presentation] Ai-CT実施に伴うCT検査室の環境調査―調査結果―2015

    • Author(s)
      稲井邦博, 西島昭彦, 飛田征男, 法木左近, 島田一郎, 岩崎博道, 内木宏延
    • Organizer
      第13回オートプシー・イメージング学会学術総会
    • Place of Presentation
      東京都, 慶応大学
    • Year and Date
      2015-08-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] Ai-CT実施に伴うCT検査室の環境調査―調査方法―2015

    • Author(s)
      西島昭彦, 稲井邦博, 飛田征男, 法木左近, 島田一郎, 岩崎博道, 内木宏延
    • Organizer
      第13回オートプシー・イメージング学会学術総会
    • Place of Presentation
      東京都, 慶応大学
    • Year and Date
      2015-08-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] 院内死亡の直接死因究明におけるオートプシー・イメージングの有効性2015

    • Author(s)
      稲井邦博, 法木左近, 木下一之, 坂井豊彦, 西島昭彦, 木村浩彦, 内木宏延
    • Organizer
      第104日本病理学会総会
    • Place of Presentation
      名古屋市, 名古屋国際会議場
    • Year and Date
      2015-04-30
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 死因究明時の感染症診断におけるオートプシー・イメージングの有用性2015

    • Author(s)
      稲井邦博, 法木左近, 岩崎博道
    • Organizer
      第89回日本感染症学会総会
    • Place of Presentation
      京都市, 京都国際会館
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] Clinical Applications of Multidisciplinary Computational Anatomy to Diagnosis -Plan of Five years and Progress Overview FY2014-2015

    • Author(s)
      S. Kido, Y. Hirano, H. Kim, H. Kimura, S. Noriki, K. Inai
    • Organizer
      The 1st International Symposium on the Project "Multidisciplinary Computational Anatomy"
    • Place of Presentation
      Hakata, Kyusyu University
    • Year and Date
      2015-02-21 – 2015-02-22
    • Related Report
      2014 Research-status Report
  • [Presentation] HPLC and HPLC-ESI-MS/MS methods for the determination of 2-acetamido-2-deoxy-D-glucopyranose analogues2014

    • Author(s)
      M.E.Martinez, Y.Tokunaga, T.Mori, A.Makino, S.Noriki, K.Inai, H.Okazawa, Y.Kiyono
    • Organizer
      Annual Congress of the European Association of Nuclear Medicine 2014
    • Place of Presentation
      Gothenburg, Sweden
    • Year and Date
      2014-10-18 – 2014-10-22
    • Related Report
      2014 Research-status Report
  • [Presentation] Bone Marrow Histiocytic Hyperplasia with Hemophagocytosis: A Critical Complication of Sepsis/ARDS2014

    • Author(s)
      K.Inai, S.Noriki, H.Naiki, H.Iwasaki
    • Organizer
      Interscience Conference on Antimicrobial Agents
    • Place of Presentation
      Washington DC, USA
    • Year and Date
      2014-09-05 – 2014-09-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Autopsy imagingを用いた教育用系統解剖遺体の病理学的解析2014

    • Author(s)
      法木左近, 稲井邦博, 木下一之, 坂井豊彦, 西島昭彦, 木村浩彦, 内木宏延, 飯野 哲
    • Organizer
      第12回オートプシー・イメージング学会学術総
    • Place of Presentation
      札幌、札幌市教育文化会館
    • Year and Date
      2014-08-31
    • Related Report
      2014 Research-status Report
  • [Presentation] オートプシー・イメージングから死後画像学への展望2014

    • Author(s)
      稲井邦博
    • Organizer
      電子情報通信学会技術研究報告─技術テーマ・招待講演─
    • Place of Presentation
      名古屋、名古屋工業大学
    • Year and Date
      2014-05-15 – 2014-05-16
    • Related Report
      2014 Research-status Report
    • Invited
  • [Book] Computational anatomy2016

    • Author(s)
      S.Noriki, K.Inai, H.Kimura
    • Publisher
      Springer
    • Related Report
      2015 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2017-05-10  

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