Polygenic analysis of intermediate phenotypes

• Project/Area Number: 26670541
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Psychiatric science
• Research Institution: Osaka University
• Principal Investigator: HASHIMOTO RYOTA 大阪大学, 連合小児発達学研究科, 准教授 (10370983)
• Co-Investigator(Kenkyū-buntansha): YASUDA Yuka 大阪大学, 医学部附属病院, 特任助教 (20448062) ; YAMAMORI Hidenaga 大阪大学, 医学系研究科, 助教 (90570250) ; FUJIMOTO Michiko 大阪大学, 医学部附属病院, 医員 (50647625) ; FUJINO Haruo 大阪大学, 人間科学研究科, 助教 (20707343) ; KUDO Noriko 大阪大学, 連合小児発達学研究科, 招へい研究員 (30751151) ; UMEDA Satomi 大阪大学, 医学系研究科, 特任研究員 (00625329)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 統合失調症 / 大脳皮質体積 / ポリジェニックリスクスコア / 中間表現型 / 遺伝子多型 / 脳MRI / 脳 MRI / MRI / SNP / 遺伝子

Outline of Final Research Achievements

It is unclear whether polygenic schizophrenia score (PSS) affects variation in specific gray matter volume (GM). PSS was calculated using another Japanese cohort. To identify brain regions related to PSS, we conducted a whole-brain search in 160 patients with schizophrenia and 378 healthy subjects using a multiple regression model. In patients, PSS was significantly negatively correlated with the local GM in the left superior temporal gyrus (STG), an area of the brain reported to have reduced GM in high-risk individuals and first-episode and chronic schizophrenia patients. Higher PSS was associated with smaller left STG volumes in patients, however, there was no effect of the score on the GM in healthy subjects. Our data demonstrating impact of genetic risk variants of schizophrenia on brain morphology could be useful for understanding pathophysiology of schizophrenia.

Research Products

• [Int'l Joint Research] Liber Institute for Brain Development(U.S.A.)
• [Int'l Joint Research] National Institute of Mental Health(U.S.A.)
• [Int'l Joint Research] Keck School of Medicine/QIMR Medical Research Institute/UCLA School of Medicine(U.S.A.)
• [Int'l Joint Research] Medical Center of the Univ of Munich/National Institute of Mental Health/Institute of Psychiatric Phenomics(Germany)
• [Journal Article] Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study. (2016)
  • Author(s): Hou L, (38名中略）Hashimoto R, (124名中40番目）（83名中略）Schulze T.G.
  • Journal Title: Lancet Volume: 12;387(10023) Issue: 10023 Pages: 1085-93
  • DOI: 10.1016/s0140-6736(16)00143-4
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Subcortical Brain Volume Abnormalities in 2,028 Individuals with Schizophrenia and 2,540 Healthy Controls via the ENIGMA Consortium. (2016)
  • Author(s): van Erp T, （54名中略)Hashimoto R,（58名中56番目）Thompson P, Turner J, for the ENIGMA Schizophrenia Working Group.
  • Journal Title: Molecular Psychiatry Volume: 21(4) Issue: 4 Pages: 547-553
  • DOI: 10.1038/mp.2015.63
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Emerging roles of ARHGAP33 in intracellular trafficking of TrkB and pathophysiology of neuropsychiatric disorders (2016)
  • Author(s): Nakazawa T, Hashimoto R, Sakoori K, Sugaya Y, Tanimura A, Hashimotodani Y, Ohi K, Yamamori H, Yasuda Y, Umeda-Yano S, Kiyama Y, Konno K, Inoue T, Yokoyama K, Inoue T, Numata S, Ohnuma T, Iwata N, Ozaki N, Hashimoto H, Watanabe M, Manabe T, Yamamoto T, Takeda M, Kano M.
  • Journal Title: Nat Communications Volume: 7 Issue: 1 Pages: 10594-10594
  • DOI: 10.1038/ncomms10594
  • NAID: 120006535052
  • URL: https://pure.teikyo.jp/en/publications/6d10cbbf-3e7f-4e5b-bfce-ab50e6dde489
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Going longitudinal in biological psychiatric research: all things considered. (2016)
  • Author(s): Gould T.D., Hashimoto R, Schulze T.G.
  • Journal Title: Neurosci Res Volume: 102(2016) Pages: 1-3
  • DOI: 10.1016/j.neures.2015.12.012
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The multidimensional anatomy of “modern type depression” in Japan: A proposal for a different diagnostic approach to depression beyond the DSM-5. (2016)
  • Author(s): Kato T, Hashimoto R, Hayakawa K, Kudo H, Watabe M, Teo A.R., Kanba S.
  • Journal Title: Psychiatry Clin Neurosci Frontier Review Volume: 70(1) Issue: 1 Pages: 7-23
  • DOI: 10.1111/pcn.12360
  • Peer Reviewed
• [Journal Article] Association of copy number polymorphisms at the promoter and translated region of COMT with Japanese patients with schizophrenia. (2015)
  • Author(s): Higashiyama R, Ohnuma T, Takebayashi Y, Hanzawa R, Shibata N, Yamamori H, Yasuda Y, Kushima I, Aleksic B, Kondo K, Ikeda M, Hashimoto R, Iwata N, Ozaki N, Arai H.
  • Journal Title: Am J Med Genet B Neuropsychiatr Genet Volume: 171 Issue: 3 Pages: 447-457
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  • Peer Reviewed / Open Access
• [Journal Article] Whole-exome sequencing and neurite outgrowth analysis in autism spectrum disorder. (2015)
  • Author(s): Hashimoto R, Nakazawa T, Tsurusaki Y, Yasuda Y, Nagayasu K, Matsumura K, Kawashima H, Yamamori H, Fujimoto M, Ohi K, Umeda-Yano S, Fukunaga M, Fujino H, Kasai A, Hayata-Takano A, Shintani N, Takeda M, Matsumoto N, Hashimoto H.
  • Journal Title: Journal of Human Genetics Volume: 61 Issue: 3 Pages: 199-206
  • DOI: 10.1038/jhg.2015.141
  • Peer Reviewed / Open Access
• [Journal Article] Impact of plasma transaminase levels on the peripheral blood glutamate levels and memory functions in healthy subjects. (2015)
  • Author(s): Kamada Y, Hashimoto R, Yamamori H, Yasuda Y, Takehara T, Fujita Y, Hashimoto K, Miyoshi E.
  • Journal Title: BBA Clin Volume: 5 Pages: 101-107
  • DOI: 10.1016/j.bbacli.2016.02.004
  • Peer Reviewed
• [Journal Article] Sensory cognitive abnormalities of pain in autism spectrum disorder: a case-control study. (2015)
  • Author(s): Yasuda Y, Hashimoto R, Nakae A, Kang H, Ohi K, Yamamori H, Fujimoto M, Hagihira S, Takeda M.
  • Journal Title: Ann Gen Psychiatry. Volume: 15：8 Issue: 1 Pages: 8-8
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  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Predicting employment status and subjective quality of life in patients with schizophrenia. (2015)
  • Author(s): Fujino H, Sumiyoshi C, Sumiyoshi T, Ysuda Y, Yamamori H, Ohi K, Fujimoto M, Hashimoto R, Takeda M, Imura O.
  • Journal Title: Schizophrenia Research: Cognition Volume: 3 Pages: 20-25
  • DOI: 10.1016/j.scog.2015.10.005
  • Peer Reviewed / Open Access
• [Journal Article] Assessment of a multi-assay biological diagnostic test for mood disorders in a Japanesepopulation. (2015)
  • Author(s): Yamamori H, Ishima T, Yasuda Y, Fujimoto M, Kudo N, Ohi K, Hashimoto K, Takeda M, Hashimoto R.
  • Journal Title: Neurosci Lett Volume: 612 Pages: 167-171
  • DOI: 10.1016/j.neulet.2015.12.019
  • Peer Reviewed / Open Access
• [Journal Article] Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val308Ile and nicotine dependence in genome-wide and subsequent association studies. (2015)
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  • Journal Title: Mol Brain. Volume: 8 Issue: 1 Pages: 50-50
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  • Peer Reviewed / Open Access
• [Journal Article] Dietary intake of sulforaphane-rich broccoli sprout extracts during juvenile and adolescence can prevent phencyclidine-induced cognitive deficits at adulthood. (2015)
  • Author(s): Shirai Y, Fujita Y, Hashimoto R, Ohi K, Yamamori H, Yasuda Y, Ishima T, Suganuma H, Ushida Y, Takeda M, Hashimoto K.
  • Journal Title: PLoS One Volume: 24 Issue: 6 Pages: e0127244-e0127244
  • DOI: 10.1371/journal.pone.0127244
  • Peer Reviewed / Open Access
• [Journal Article] Sex differences of leukocytes DNA methylation adjusted for estimated cellular proportions. (2015)
  • Author(s): Inoshita M, Numata S, Tajima A, Kinoshita M, Umehara H, Yamamori H, Hashimoto R, Imoto I, Ohmori T.
  • Journal Title: Biol Sex Differ. Volume: 6 Issue: 1 Pages: 11-11
  • DOI: 10.1186/s13293-015-0029-7
  • NAID: 120005646687
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Atomoxetine reverses locomotor hyperactivity, impaired novel object recognition, and prepulse inhibition impairment in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP). (2015)
  • Author(s): hibasaki Y, Hayata-Takano A, Hazama K, Nakazawa T, Shintani N, Kasai A, Nagayasu K, Hashimoto R, Tanida M, Katayama T, Matsuzaki S, Yamada K, Taniike M, Onaka Y, Ago Y, Waschek JA, Köves K, Reglődi D, Tamas A, Matsuda T, Baba A, Hashimoto H.
  • Journal Title: Neuroscience Volume: 297 Pages: 95-104
  • DOI: 10.1016/j.neuroscience.2015.03.062
  • Peer Reviewed
• [Journal Article] The piccolo intronic single nucleotide polymorphism rs13438494 regulates dopamine and serotonin uptake and shows associations with dependence-like behavior in genomic association study. (2015)
  • Author(s): Uno K, Nishizawa D, Seo S, Takayama K, Matsumura S, Sakai N, Ohi K, Nabeshima T, Hashimoto R, Ozaki N, Hasegawa J, Sato N, Tanioka F, Sugimura H, Fukuda K, Higuchi S, Ujike H, Inada T, Iwata N, Sora I, Iyo M, Kondo N, Won M-J, Naruse N, Uehara K, Itokawa M, Yamada M, Ikeda K, Miyamoto Y, Nitta A.
  • Journal Title: Current molecular medicine Volume: 15(3) Issue: 3 Pages: 265-274
  • DOI: 10.2174/1566524015666150330145722
  • Peer Reviewed
• [Journal Article] p13 overexpression in pancreatic b-cells ameliorates type 2 diabetes in high-fat-fed mice (2015)
  • Author(s): Higashi, S. et al.
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 461 Issue: 4 Pages: 612-617
  • DOI: 10.1016/j.bbrc.2015.04.074
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Standing postural instability in patients with schizophrenia: Relationships with psychiatric symptoms, anxiety, and the use of neuroleptic medications (2015)
  • Author(s): Matsuura Y, Fujino H, Hashimoto R, Yasuda Y, Yamamori H, Ohi K, Takeda M, Imura O.
  • Journal Title: Gait & Posture Volume: in press Issue: 3 Pages: 847-851
  • DOI: 10.1016/j.gaitpost.2015.03.006
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain. (2015)
  • Author(s): Ohi K, Ursini G, Li M, Shin J.H.,Ye T, Chen Q, Tao R, Kleinman JE., Hyde TM., Hashimoto R, Weinberger DR.
  • Journal Title: Transl Psychiatry Volume: 14;5 Issue: 4 Pages: e550-e550
  • DOI: 10.1038/tp.2015.45
  • Peer Reviewed / Open Access
• [Journal Article] Common genetic variants influence human subcortical brain structures (2015)
  • Author(s): Hibar P ,,,, Ikeda M,,,,et al
  • Journal Title: Nature Volume: 520 Issue: 7546 Pages: 224-9
  • DOI: 10.1038/nature14101
  • Peer Reviewed
• [Journal Article] Imaging genetics and psychiatric disorders. (2015)
  • Author(s): Hashimoto R, Kazutaka Ohi, Yamamori H, Yasuda Y, Fujimoto M, Umeda-Yano S, Watanabe Y, Fukunaga M, Takeda M.
  • Journal Title: Current Molecular Medicine. Volume: 15(2) Issue: 2 Pages: 168-175
  • DOI: 10.2174/1566524015666150303104159
  • Peer Reviewed
• [Journal Article] Simultaneous neuron- and astrocyte-specific fluorescent marking. (2015)
  • Author(s): Schulze W, Hayata-Takano A, Kamo T, Nakazawa T, Nagayasu K, Kasai A, Seiriki K, Shintani N, Ago Y, Farfan C, Hashimoto R, Baba A, Hashimoto H.
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 459 Issue: 1 Pages: 81-86
  • DOI: 10.1016/j.bbrc.2015.02.073
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Identification of the role of BMP and TGF-β signaling in the trajectory of serotonergic differentiation in a rapid assay in mouse embryonic stem cells in vitro. (2015)
  • Author(s): Yamasaki A, Kasai A, Toi A, Kurita M, Kimoto S, Hayata-Takano A, Nakazawa T, Nagayasu K, Shintani N, Hashimoto R, Ito A, Meltzer HY, Ago Y, Waschek JA, Onaka Y, matsuda T, Baba A, Hashimoto H.
  • Journal Title: Journal of Neurochemistry, Volume: 132(4) Issue: 4 Pages: 418-428
  • DOI: 10.1111/jnc.12999
  • Peer Reviewed / Open Access
• [Journal Article] CRTH2, a prostaglandin D2 receptor, mediates depression-related behavior in mice (2015)
  • Author(s): Yusuke Onaka, Norihito Shintani, Takanobu Nakazawa, Ryota Haba, Yukio Ago, Hyper Wang, Takuya Kanoh, Atsuko Hayata-Takano, Hiroyuki Hirai, Kin-ya Nagata, Masataka Nakamura, Ryota Hashimoto, Toshio Matsuda, James A. Waschek, Atsushi Kasai, Kazuki Nagayasu, Akemichi Baba, Hitoshi Hashimoto
  • Journal Title: Behavioural Brain Research Volume: 284 Pages: 131-137
  • DOI: 10.1016/j.bbr.2015.02.013
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Genetic overlap between antipsychotic response and susceptibility to schizophrenia (2015)
  • Author(s): Ikeda M, Yoshimura R, Hashimoto R, Kondo K, Saito T, Shimasaki A, Ohi K, Tochigi M, Kawamura Y, Nishida N, Miyagawa T, Sasaki T, Tokunaga K, Kasai K, Takeda M, Nakamura J, Ozaki N, Iwata N.
  • Journal Title: Journal of Clinical Psychopharmacology Volume: 35(1) Issue: 1 Pages: 85-88
  • DOI: 10.1097/jcp.0000000000000268
  • Peer Reviewed / Open Access
• [Journal Article] Glutamate Networks Implicate Cognitive Impairments in Schizophrenia: Genome-Wide Association Studies of 52 Cognitive Phenotypes. (2014)
  • Author(s): Ohi K, Hashimoto R, Ikeda M, Yamamori H, Yasuda Y, Fujimoto M, Umeda-Yano S, Fukunaga M, Fujino H, Watanabe Y, Iwase M, Kazui H, Iwata N, Weinberger DR, Takeda M.
  • Journal Title: Schizophr Bull. Volume: 41 Issue: 4 Pages: 909-18
  • DOI: 10.1093/schbul/sbu171
  • NAID: 40020682401
  • Peer Reviewed / Open Access
• [Journal Article] An integrated eye movement score as a neurophysiological marker of schizophrenia (2014)
  • Author(s): Miura K, Hashimoto R, Fujimoto M, Yamamori H, Yasuda Y, Ohi K, Umeda-Yano S, Fukunaga M, Iwase M, Takeda M
  • Journal Title: Schizophrenia Research Volume: 160(1-3) Issue: 1-3 Pages: 228-9
  • DOI: 10.1016/j.schres.2014.10.023
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Failure of replicating the association between hippocampal volume and 3 single-nucleotide polymorphisms identified from theEuropean genome-wide association study in Asian populations. (2014)
  • Author(s): Li M, Ohi K, Chen C, He Q, Lu JW, Chen C. Luo XJ, Dong Q, Hashimoto R, Su B.
  • Journal Title: Neurobiology of Aging, Volume: 35(12) Issue: 12 Pages: 2883.e1-2883.e2
  • DOI: 10.1016/j.neurobiolaging.2014.07.015
  • Peer Reviewed
• [Journal Article] Aberrant DNA methylation of blood in schizophrenia by adjusting for estimated cellular proportions (2014)
  • Author(s): Kinoshita M, Numata S, Tajima A, Ohi K, Hashimoto R, Shimodera S, Imoto I, Takeda M, Ohmori T
  • Journal Title: NeuroMolecular Medicine Volume: 16 Issue: 4 Pages: 697-703
  • DOI: 10.1007/s12017-014-8319-5
  • Peer Reviewed
• [Journal Article] Behavioral characterization of mice overexpressing human dysbindin-1 (2014)
  • Author(s): Shintani N, Onaka Y, Hashimoto R, Takamura H, Nagata T, Umeda-Yano S, Mouri A, Mamiya T, Haba R, Matsuzaki S, Katayama T, Yamamori H, Nakazawa T, Nagayasu K, Ago Y, Yagasaki Y, Nabeshima T, Takeda M, Hashimoto H
  • Journal Title: Molecular Brain Volume: 7(1) Issue: 1 Pages: 74-74
  • DOI: 10.1186/s13041-014-0074-x
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Common variants at 1p36 are associated with superior frontal gyrus volume. (2014)
  • Author(s): Hashimoto R, Ikeda M, Yamashita F, Ohi K, Yamamori H, Yasuda Y, Fujimoto M, Fukunaga M, Nemoto K, Takahashi T, Tochigi M, Onitsuka T, Yamasue H, Matsuo K, Iidaka T, Iwata N, Suzuki M, Takeda M, Kasai K, Ozaki N
  • Journal Title: Translational Psychiatry Volume: 4 Issue: 10 Pages: e472-e472
  • DOI: 10.1038/tp.2014.110
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Opioid therapy for knee osteoarthritis and postoperative persistent pain after knee arthroplasty (2014)
  • Author(s): Miki K, Hashimoto R, Shi K, Yukioka M,
  • Journal Title: Rheumatology Volume: 53(10) Issue: 10 Pages: 1723-24
  • DOI: 10.1093/rheumatology/keu309
  • Peer Reviewed
• [Journal Article] RacGAP α2-chimaerin function in development adjusts cognitive ability in adulthood (2014)
  • Author(s): Iwata R, Ohi K, Kobayashi Y, Masuda A, Masuda A, Iwama M, Yasuda Y, Yamamori H, Tanaka M, Hashimoto R, Itohara S, Iwasato T
  • Journal Title: Cell Report Volume: 8(5) Issue: 5 Pages: 1257-64
  • DOI: 10.1016/j.celrep.2014.07.047
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Changes in plasma D-serine, L-serine, and glycine levels in treatment-resistant schizophrenia before and after clozapine treatment. (2014)
  • Author(s): Yamamori H, Hashimoto R, Fujita Y, Numata S, Yasuda Y, Fujimoto M, Ohi K, Umeda-Yano S, Ito A, Ohmori T, Hashimoto K, Takeda M.
  • Journal Title: Neurosci Lett. Volume: 582 Pages: 93-8
  • DOI: 10.1016/j.neulet.2014.08.052
  • Peer Reviewed
• [Journal Article] Meta-analyses of blood homocysteine levels for gender and genetic association studies of the MTHFR C677T polymorphism in schizophrenia (2014)
  • Author(s): Nishi A, Numata S, Tajima A, Kinoshita M, Kikuchi K, Shimodera S, Tomotake M, Ohi K, Hashimoto R, Imoto I, Takeda M, Ohmori T
  • Journal Title: Schizophrenia Bulletin Volume: 40(5) Issue: 5 Pages: 1154-63
  • DOI: 10.1093/schbul/sbt154
  • Peer Reviewed / Open Access
• [Journal Article] Duplication of the NPHP1 gene in patients with autism spectrum disorder and normal intellectual ability: a case series. (2014)
  • Author(s): Yasuda Y, Hashimoto R, Fukai R, Okamoto N, Hiraki Y, Yamamori H, Fujimoto M, Ohi K, Taniike M, Mohri I, Nakashima M, Tsurusaki Y, Saitsu H, Matsumoto N, Miyake N, Takeda M.
  • Journal Title: Ann Gen Psychiatry. Volume: 13 Issue: 1 Pages: 22-26
  • DOI: 10.1186/s12991-014-0022-2
  • Peer Reviewed / Open Access
• [Journal Article] Neuromelanin magnetic resonance imaging reveals increased dopaminergic neuron activity in the substantia nigra of patients with schizophrenia. (2014)
  • Author(s): Watanabe Y, Tanaka H, Tsukabe A, Kunitomi Y, Nishizawa M, Hashimoto R, Yamamori H, Fujimoto M, Fukunaga M, Tomiyama N.
  • Journal Title: PLoS One Volume: 9 Issue: 8 Pages: e104619-e104619
  • DOI: 10.1371/journal.pone.0104619
  • Peer Reviewed / Open Access
• [Journal Article] Performance on the Wechsler Adult Intelligence Scale-III in Japanese patients with schizophrenia. (2014)
  • Author(s): Fujino H, Sumiyoshi C, Sumiyoshi T, Yasuda Y, Yamamori H, Ohi K, Fujimoto M, Umeda-Yano S, Higuchi A, Hibi Y, Matsuura Y, Hashimoto R, Takeda M, Imura O.
  • Journal Title: Psychiatry Clin Neurosci. Volume: in press Issue: 7 Pages: 534-541
  • DOI: 10.1111/pcn.12165
  • Peer Reviewed
• [Journal Article] Cognitive inflexibility in Japanese adolescents and adults with autism spectrum disorders. (2014)
  • Author(s): Yasuda Y, Hashimoto R, Ohi K, Yamamori H, Fujimoto M, Umeda-Yano S, Fujino H, Takeda M.
  • Journal Title: World J Psychiatry. Volume: 22 Issue: 2 Pages: 42-8
  • DOI: 10.5498/wjp.v4.i2.42
  • Peer Reviewed / Open Access
• [Journal Article] Association between genetic polymorphism rs2952768, close to the METTL21A and CREB1 genes, and intellectual ability in healthy subjects (2014)
  • Author(s): Nishizawa D, Ohi K, Hashimoto R, Yamamori H, Yasuda Y, Fujimoto M, Umeda-Yano S, Takeda M, Ikeda K
  • Journal Title: Journal of Addiction Research & Therapy Volume: 5(2) Issue: 02 Pages: 1000178-1000178
  • DOI: 10.4172/2155-6105.1000178
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Genetic risk variants of schizophrenia associated with left superior temporal gyrus volume. (2014)
  • Author(s): Ohi K, Hashimoto R, Ikeda M, Yamashita F, Fukunaga M, Nemoto K, Ohnishi T, Yamamori H, Yasuda Y, Fujimoto M, Umeda-Yano S, Watanabe Y, Iwata N, Weinberger DR, Takeda M.
  • Journal Title: Cortex Volume: 58 Pages: 23-6
  • DOI: 10.1016/j.cortex.2014.05.011
  • Peer Reviewed / Open Access
• [Journal Article] A functional polymorphism (C-824T) of the tyrosine hydroxylase gene affects intelligence quotient in schizophrenia (2014)
  • Author(s): Horiguchi M, Ohi K, Hashimoto R, Hao Q, Yasuda Y, Yamamori H, Fujimoto M, Umeda-Yano S, Takeda M, Ichinose H
  • Journal Title: Psychiatry and Clinical Neurosciences Volume: 68(6) Issue: 6 Pages: 456-62
  • DOI: 10.1111/pcn.12157
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Differential Effects of Common Variants in SCN2A on General Cognitive Ability, (2014)
  • Author(s): Dickinson D, Straub RE, Trampush JW, Gao Y, Feng N, Xie B, Shin JH, Lim HK, Ursini G, Bigos KL, Kolachana B, Hashimoto R, Takeda M, Baum GL, Rujescu D, Callicott JH, Hyde TM, Berman KF, Kleinman JE, Weinberger DR.
  • Journal Title: JAMA Psychiatry Volume: 1;71(6) Issue: 6 Pages: 647-56
  • DOI: 10.1001/jamapsychiatry.2014.157
  • Peer Reviewed
• [Journal Article] Direct induction of ramified microglia-like cells from human monocytes: Dynamic microglial dysfunction in Nasu-Hakola disease. (2014)
  • Author(s): Ohgidani M, Kato TA*, Setoyama D, Sagata N, Hashimoto R, Shigenobu K, Yoshida T, Hayakawa K, Shimokawa N, Miura D, Utsumi H, Kanba S
  • Journal Title: Scientific Reports Volume: 4 Issue: 1 Pages: 4957-4957
  • DOI: 10.1038/srep04957
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Presentation] 統合失調症の皮質下体積と認知・社会機能の相関解析 (2016)
  • Author(s): 越山太輔、福永雅喜、岡田直大、山森英長、安田由華、藤本美智子、山下典生、藤野陽生、渡邉嘉之、住吉チカ、住吉太幹、笠井清登、橋本亮太
  • Organizer: 第11回日本統合失調症学会
  • Place of Presentation: 群馬
  • Year and Date: 2016-03-25
• [Presentation] ENIGMA-SZJ：統合失調症の皮質下体積のメタアナリシス (2016)
  • Author(s): 岡田直大、福永雅喜、山下典生、越山太輔、山森英長、安田由華、渡邉嘉之、根本清貴、橋本直樹、宮田淳、山末英典、松尾幸治、鬼塚俊明、川崎康弘、吉村玲児、鈴木道雄、武田雅俊、尾崎紀夫、笠井清登、橋本亮太
  • Organizer: 第11回日本統合失調症学会
  • Place of Presentation: 群馬
  • Year and Date: 2016-03-25
• [Presentation] 統合失調症における補助診断ツールとしての眼球運動スコアの妥当性 (2016)
  • Author(s): 森田健太郎、三浦健一郎、藤本美智子、山森英長、安田由華、笠井清登、橋本亮太
  • Organizer: 第11回日本統合失調症学会
  • Place of Presentation: 群馬
  • Year and Date: 2016-03-25
• [Presentation] CPC-JとBPHUBの運営・サンプル管理・拡充と研究統括 (2016)
  • Author(s): 橋本亮太
  • Organizer: 日本医療研究開発機構 平成27年度障害者対策総合研究開発事業（精神障害分野）「治療抵抗性統合失調症に対する客観的診断・治療法の開発」成果報告会
  • Place of Presentation: 大阪
  • Year and Date: 2016-03-19
• [Presentation] ゲノム科学による霊長類脳の多様性の解明 (2016)
  • Author(s): 橋本亮太、中澤敬信、岡田直大、安田由華、山森英長、松村憲佑、永安一樹、藤本美智子、三浦健一郎、福永雅喜、笠井清登、橋本均
  • Organizer: 平成27年度 京都大学霊長類研究所共同利用研究会「霊長類脳科学の新しい展開とゲノム科学との融合」
  • Place of Presentation: 犬山
  • Year and Date: 2016-03-11
• [Presentation] ポリジェニック脳神経画像解析による統合失調症の早期診断法の開発の概略 (2015)
  • Author(s): 橋本亮太
  • Organizer: 日本医療研究開発機構 平成27年度障害者対策総合研究開発事業（精神障害分野）合同班会議
  • Place of Presentation: 東京
  • Year and Date: 2015-12-19
• [Presentation] オーガナイザー、サイエンスコミュニケーション「研究者の社会的役割」 (2015)
  • Author(s): 橋本亮太
  • Organizer: 包括型脳科学研究推進支援ネットワーク冬のシンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2015-12-17
• [Presentation] 精神疾患とその偏見への挑戦-こころの扉を開き克服するまで- (2015)
  • Author(s): 橋本亮太
  • Organizer: 第256回徳島精神科臨床懇話会
  • Place of Presentation: 徳島
  • Year and Date: 2015-12-16
• [Presentation] 発達障害・統合失調症等の克服に関する研究について① (2015)
  • Author(s): 橋本亮太
  • Organizer: 脳科学の新しい推進プログラムに関する検討会
  • Place of Presentation: 東京
  • Year and Date: 2015-11-29
• [Presentation] 多施設共同研究体制の構築 (2015)
  • Author(s): 橋本亮太
  • Organizer: 第6回脳表現型の分子メカニズム研究会
  • Place of Presentation: 東京
  • Year and Date: 2015-11-14
• [Presentation] 統合失調症の脳画像・生理・認知行動解析による病態神経回路解明 (2015)
  • Author(s): 橋本亮太
  • Organizer: 平成27年度脳科学研究戦略推進プログラム・革新的技術による脳機能ネットワークの全容解明プロジェクト進捗報告会
  • Place of Presentation: 東京
  • Year and Date: 2015-11-05
• [Presentation] CPC-J （日本クロザピン薬理ゲノム学コンソーシアム）、クロザピン誘発性無顆粒球症・顆粒球減少症に関する薬理ゲノム学的研究 (2015)
  • Author(s): 齋藤竹生、池田匡志、莚田泰誠、大関健志、近藤健治、島崎愛夕、川瀬康平、山森英長、安田由華、藤本美智子、大井一高、武田雅俊、橋本亮太、岩田仲生
  • Organizer: 第25回日本臨床精神神経薬理学会
  • Place of Presentation: 東京
  • Year and Date: 2015-10-29
• [Presentation] The effect of blood cellular heterogeneity on DNA methylation in schizophrenia. (2015)
  • Author(s): Numata S, Kinoshita M, Tajima A, Ohi K, Hashimoto R, Shimodera S, Imoto I, Takeda M, Ohmori T.
  • Organizer: Society of neuroscience
  • Place of Presentation: Chicago U.S.A.
  • Year and Date: 2015-10-17
• [Presentation] Pharmacogenomics analysis identifies HLA-DRB1 as a risk for Lamotrigine-induced cutaneous adverse drug reactions in a Japanese population. (2015)
  • Author(s): Saito T, Ikda M, Kondo K, Shimasaki A, Kawase K, Hayashi T, Takahashi Y, Hashimoto R, Iwata N.
  • Organizer: The 2015 World Congress of Psychiatric Genetics
  • Place of Presentation: Toronto, Canada
  • Year and Date: 2015-10-16
• [Presentation] CPC-JとBPHUBの運営・サンプル管理・拡充と研究統括 (2015)
  • Author(s): 橋本亮太
  • Organizer: 日本医療研究開発機構 平成27年度障害者対策総合研究開発事業（精神障害分野）「治療抵抗性統合失調症に対する客観的診断・治療法の開発」第一回班会議
  • Place of Presentation: 大阪
  • Year and Date: 2015-10-09
• [Presentation] 線維筋痛症の精神医学的アプローチによる鑑別診断・構造化治療とそのコツ―、教育講演「線維筋痛症の鑑別診断と治療の実際」 (2015)
  • Author(s): 橋本亮太
  • Organizer: 日本線維筋痛症学会第7回学術集会
  • Place of Presentation: 東京
  • Year and Date: 2015-10-03
• [Presentation] 統合失調症の薬物治療ガイドライン 第四章：「治療抵抗性」概説 (2015)
  • Author(s): 橋本亮太、諏訪太郎、嶽北佳輝、三澤史斉、宮田量治、榎本哲郎
  • Organizer: シンポジウム,第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
  • Place of Presentation: 東京
  • Year and Date: 2015-09-24
• [Presentation] 大規模臨床研究を推進するための体制について、日本における大規模臨床研究のCOCOROによる実践 (2015)
  • Author(s): 橋本亮太
  • Organizer: シンポジウム19：第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
  • Place of Presentation: 東京
  • Year and Date: 2015-09-24
• [Presentation] 精神疾患における客観的な補助診断法の最前線、眼球運動を用いた統合失調症の客観的補助診断法 (2015)
  • Author(s): 三浦健一郎、橋本亮太、藤本美智子、山森英長、安田由華、藤野陽生、福永雅喜、武田雅俊
  • Organizer: シンポジウム22：第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
  • Place of Presentation: 東京
  • Year and Date: 2015-09-24
• [Presentation] 精神疾患における客観的な補助診断法の最前線、精神疾患における客観的な補助診断法の今後の方向性 (2015)
  • Author(s): 橋本亮太、山森英長、安田由華、藤本美智子、藤野陽生、三浦健一郎、福永雅喜、武田雅俊
  • Organizer: シンポジウム22：第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
  • Place of Presentation: 東京
  • Year and Date: 2015-09-24
• [Presentation] 統合失調症における補助診断ツールとしての眼球運動スコアの有用性 (2015)
  • Author(s): 藤本美智子、橋本亮太、三浦健一郎、山森英長、安田由華、大井一高、岩瀬真生、武田雅俊
  • Organizer: 第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
  • Place of Presentation: 東京
  • Year and Date: 2015-09-24
• [Presentation] 複数のバイオマーカーを用いた統合失調症の補助診断方法確立の検討 (2015)
  • Author(s): 山森英長、橋本亮太、石間環、藤本美智子、安田由華、大井一高、新津富央、沼田周助、大森哲郎、伊豫雅臣、橋本謙二、武田雅俊
  • Organizer: 第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
  • Place of Presentation: 東京
  • Year and Date: 2015-09-24
• [Presentation] 統合失調の皮質下体積と認知機能の相関解析 (2015)
  • Author(s): 越山太輔、福永雅喜、岡田直大、山下典生、山森英長、安田由華、藤本美智子、大井一高、藤野陽生、笠井清登、橋本亮太
  • Organizer: 第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
  • Place of Presentation: 東京
  • Year and Date: 2015-09-24
• [Presentation] ENIGMA-SZJ：統合失調症の皮質下体積のメタアナリシス (2015)
  • Author(s): 岡田直大、福永雅喜、山下典生、越山太輔、山森英長、大井一高、安田由華、藤本美智子、渡邉嘉之、八幡憲明、根本清貴、磯部昌憲、磯村周一、夏堀龍暢、成田尚、橋本直樹、宮田淳、小池進介、高橋努、山末英典、松尾幸治、鬼塚俊明、飯高哲也、吉村玲児、渡邉義文、鈴木道雄、武田雅俊、尾崎紀夫、笠井清登、橋本亮太
  • Organizer: 第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
  • Place of Presentation: 東京
  • Year and Date: 2015-09-24
• [Presentation] Research Domain Criteria (RDoC)の立場から未来への展望 (2015)
  • Author(s): 橋本亮太
  • Organizer: メインシンポジウム「精神科診断学のあるべき方向性」、第35回日本精神科診断学会
  • Place of Presentation: 北海道
  • Year and Date: 2015-08-06
  • Invited
• [Presentation] 統合失調症の認知機能障害へのグルタミン酸ネットワークの関与：52の認知表現型の全ゲノム関連解析 (2015)
  • Author(s): 橋本亮太、大井一高、池田匡志、山森英長、安田由華、藤本美智子、梅田知美、福永雅喜、藤野陽生、渡邊嘉之、岩瀬真生、数井裕光、岩田仲生、Daniel R. Weinberger.
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸
  • Year and Date: 2015-07-28
• [Presentation] 社会機能は統合失調症患者の主観的QoLを予測する (2015)
  • Author(s): 藤野陽生、住吉チカ、住吉太幹、安田由華、山森英長、大井一高、藤本美智子、橋本亮太、武田雅俊、井村修
  • Organizer: 第38回日本神経科学大会
  • Place of Presentation: 神戸
  • Year and Date: 2015-07-28
• [Presentation] Comorbidity of psychiatric disorders in chronic pain. (2015)
  • Author(s): Hashimoto R, Yasuda Y, Nakae A, Yamamori H, Fujimoto M, Ohi K, Kou K, Hagihira S, Miki K, Yukioka M, Takeda M.
  • Organizer: Symposium S-41: 12th World Congress of Biological Psychiatry 2015
  • Place of Presentation: Athens, Greece
  • Year and Date: 2015-06-14
  • Invited
• [Presentation] Intermediate phenotype strategy for discovering disease related gene network. (2015)
  • Author(s): Hashimoto R, Ohi K, Ikeda M, Yamamori H, Yasuda Y, Fujimoto M, Fukunaga M, Fujino H, Watanabe Y, Iwata N, Takeda M.
  • Organizer: Symposium S-55: 12th World Congress of Biological Psychiatry 2015
  • Place of Presentation: Athens, Greece
  • Year and Date: 2015-06-14
  • Invited
• [Presentation] Predicting social functioning and subjective quality of life in patients with schizophrenia. (2015)
  • Author(s): Fujino H, Sumiyoshi C, Sumiyoshi T, Yasuda Y, Yamamori H, Ohi K, Fujimoto M, Hashimoto R, Takeda M, Imura O.
  • Organizer: WPA regional congress
  • Place of Presentation: Osaka, Japan
  • Year and Date: 2015-06-04
• [Presentation] 精神医学英語論文の書き方－正しく、美しく、効率的に－、教育講演19 (2015)
  • Author(s): 橋本亮太
  • Organizer: 第111回日本精神神経学会学術総会
  • Place of Presentation: 大阪
  • Year and Date: 2015-06-04
• [Presentation] Japanese-German Neuroscience Research Network Focusing on Psychosis, Affective Disorders & Related Traits: Genomewide association study of intermediate phenotypes. (2015)
  • Author(s): Hashimoto R
  • Organizer: 第４回日独6大学学長会議
  • Place of Presentation: 仙台
  • Year and Date: 2015-04-16
• [Presentation] 統合失調症の眼球運動異常-補助診断法の開発へ- (2015)
  • Author(s): 橋本亮太、三浦健一郎、藤本美智子、山森英長、安田由華、大井一高、福永雅喜, 武田雅俊、
  • Organizer: 第10回統合失調症学会
  • Place of Presentation: 東京
  • Year and Date: 2015-03-27 – 2015-03-28
• [Presentation] 霊長類におけるゲノムによる脳機能の多様性の解明 (2015)
  • Author(s): 橋本亮太、中澤敬信、今井啓雄、井上謙一、安田由華、山森英長、大井一高、松村憲佑、永安一樹、三浦健一郎、福永雅喜、高田昌彦、武田雅俊、橋本均、
  • Organizer: 平成26年度新分野創成センターブレインサイエンス研究分野プロジェクト成果発表会
  • Place of Presentation: 東京
  • Year and Date: 2015-03-24
• [Presentation] ゲノム科学による霊長類脳の多様性の解明 (2015)
  • Author(s): 橋本亮太、中澤敬信、今井啓雄、井上謙一、安田由華、山森英長、大井一高、松村憲佑、永安一樹、三浦健一郎、福永雅喜、高田昌彦、武田雅俊、橋本均、
  • Organizer: 2015京大霊長研共同利用研究
  • Place of Presentation: 岡崎
  • Year and Date: 2015-03-14
• [Presentation] Acceptable English Papers as a PCN editor (2015)
  • Author(s): Hashimoto R, et al
  • Organizer: The 5th World Congress of Asian Psychiatry(WCAP2015)第5回アジア精神医学会
  • Place of Presentation: Fukuoka, Japan
  • Year and Date: 2015-03-04
  • Invited
• [Presentation] 精神疾患の客観的補助診断法の開発研究 (2015)
  • Author(s): 橋本亮太、他
  • Organizer: 2015脳プロ公開シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2015-02-07
• [Presentation] 統合失調症の認知機能障害の全ゲノム関連解析 (2015)
  • Author(s): 橋本亮太
  • Organizer: SCBR（Schizophrenia Clinical and Basic Research）FORUM 201
  • Place of Presentation: 東京
  • Year and Date: 2015-01-31
• [Presentation] 精神疾患の中間表現型研究 (2014)
  • Author(s): 橋本亮太
  • Organizer: 日本神経精神薬理学会第三回学術奨励賞受賞記念講演
  • Place of Presentation: 名古屋
  • Year and Date: 2014-11-21
  • Invited
• [Presentation] 統合失調症の認知機能障害の全ゲノム関連解析 (2014)
  • Author(s): 橋本亮太、池田匡志、大井一高、安田由華、山森英長、福本素由己、梅田知美、Dickinson D、Aleksic B.、岩瀬真生、数井裕光、尾崎紀夫、Weinberger DR、岩田仲生、武田雅俊、
  • Organizer: 第59回日本人類遺伝学会 第21回日本遺伝子診療学会合同大会
  • Place of Presentation: 東京
  • Year and Date: 2014-11-20 – 2014-11-21
• [Presentation] 統合失調症患者の認知機能障害の簡易測定法の開発 (2014)
  • Author(s): 橋本亮太、住吉チカ、藤野陽生、山森英長、藤本美智子、安田由華、大井一高、井村修、住吉太幹、武田雅俊、
  • Organizer: 第14回精神疾患と認知機能研究会
  • Place of Presentation: 東京
  • Year and Date: 2014-11-08
  • Invited
• [Presentation] 統合失調症患者由来サンプルを用いた統合失調症の病態解明研究 (2014)
  • Author(s): 橋本亮太、山森英長、梅田知美、藤本美智子、安田由華、伊藤彰、武田雅俊、
  • Organizer: 第11回NDDC-JSG会議
  • Place of Presentation: 大阪
  • Year and Date: 2014-10-07
• [Presentation] 神経化学が読み解く精神疾患の病態メカニズム (2014)
  • Author(s): 橋本亮太、
  • Organizer: 第7 回（2014 年）神経化学の若手研究者育成セミナー
  • Place of Presentation: 奈良
  • Year and Date: 2014-09-29 – 2014-10-01
• [Presentation] 我が国の発達障害研究はトランスレーショナルとなりうるか？ (2014)
  • Author(s): 橋本亮太、安田由華、山森英長、大井一高、藤本美智子、梅田知美、武田雅俊、
  • Organizer: 第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
  • Place of Presentation: 奈良
  • Year and Date: 2014-09-29 – 2014-10-01
• [Presentation] ビッグサイエンスに対する挑戦：スモールサイエンスと基礎研究の融合 (2014)
  • Author(s): 橋本亮太、大井一高、山森英長、安田由華、藤本美智子、梅田知美、武田雅俊、
  • Organizer: 第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
  • Place of Presentation: 奈良
  • Year and Date: 2014-09-29 – 2014-10-01
• [Presentation] 精神疾患とその偏見への挑戦：こころの扉を開き克服するまで (2014)
  • Author(s): 橋本亮太
  • Organizer: 新適塾「脳はおもしろい」第6回
  • Place of Presentation: 大阪
  • Year and Date: 2014-09-17
  • Invited
• [Presentation] 精神疾患分野から-多施設共同研究による倫理的問題点- (2014)
  • Author(s): 橋本亮太
  • Organizer: ヒトゲノム解析研究倫理審査を考える会
  • Place of Presentation: 東京
  • Year and Date: 2014-08-03
  • Invited
• [Presentation] Intermediate phenotype studies in schizophrenia (2014)
  • Author(s): Hashimoto R, Ohi K, Yamamori H, Yasuda Y, Fujimoto M, Umeda-Yano S, Takeda M.
  • Organizer: 29th CINP World Congress of Neuropsychopharmacology
  • Place of Presentation: Vancouver, Canada
  • Year and Date: 2014-06-23
  • Invited
• [Presentation] 治療抵抗性統合失調症への果てしなき挑戦：治療のゴールはどこにあるのか？ (2014)
  • Author(s): 橋本亮太、山森英長、藤本美智子、安田由華、大井一高、梅田知美、武田雅俊、
  • Organizer: 第110回日本精神神経学会学術総会
  • Place of Presentation: 横浜
  • Year and Date: 2014-06-07
• [Book] ディメンジョナルな捉え方, RDoCの紹介、月刊精神科 (2016)
  • Author(s): 橋本亮太、若菜茂晴
  • Publisher: 科学評論社
• [Book] Conference Report:第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会-シンポジウム「統合失調症の薬物治療ガイドライン」に参加して-、精神科臨床Legato (2016)
  • Author(s): 越山太輔、橋本亮太
  • Publisher: メディカルレビュー社
• [Book] 精神疾患の中間表現型研究、日本神経精神薬理学雑誌 (2016)
  • Author(s): 橋本亮太
  • Publisher: 日本神経精神薬理学会
• [Book] Intermediate phenotypes approach for neuropsychiatric disorders. Neurodegenerative Disorder as Systematic Diseases (2015)
  • Author(s): Ohi K, Hashimoto R, Yamamori H, Yasuda Y, Fujimoto M, Umeda-Yano S, Takeda M.
  • Publisher: Springer
• [Book] グルタミン酸ネットワークが統合失調症の認知機能障害に関与する; 52種類の認知機能の全ゲノム関連研究、精神医学 (2015)
  • Author(s): 大井一高、橋本亮太、山森英長、安田由華、藤本美智子、武田雅俊
  • Publisher: 医学書院
• [Book] 精神疾患にける認知機能障害の遺伝基盤、精神科治療学 (2015)
  • Author(s): 大井一高、橋本亮太
  • Publisher: 星和書店
• [Book] 統合失調症の認知機能障害の神経科学基盤、臨床精神薬理 (2015)
  • Author(s): 藤野陽生、安田由華、山森英長、藤本美智子、大井一高、福永雅喜、武田雅俊、橋本亮太
  • Publisher: 星和書店
• [Book] JSNP Excellent Presentation Award for CINP 2014:ゲノムワイド及び追加関連解析によるニコチン依存関連遺伝子多型の同定、日本神経精神薬理学雑誌 (2015)
  • Author(s): 西澤大輔、笠井慎也、長谷川準子、佐藤直美、谷岡書彦、長島誠、氏家寛、橋本亮太、田中雅嗣、椙村春彦、池田和隆
  • Publisher: 日本神経精神薬理学会
• [Book] JSNP Excellent Presentation Award for CINP 2014:PCLOのSNPrs1348494は転写効率を制御することによりモノアミンの取り込み能を調整し、ヒト依存様行動と遺伝的関連性がある、日本神経精神薬理学雑誌、 (2015)
  • Author(s): 宇野恭介、西澤大輔、徐承姫、酒井規雄、大井一高、鍋島俊隆、橋本亮太、尾崎紀夫、池田和隆、宮本嘉明、新田淳美
  • Publisher: 日本神経精神薬理学会
• [Book] Imaging Genetics、ゲノム医科学と精神医学：分子精神医学 (2015)
  • Author(s): 大井一高、橋本亮太、安田由華、山森英長、藤本美智子、武田雅俊
  • Publisher: 先端医学社
• [Book] 双極性障害のAldaスケール、精神・心理機能評価ハンドブック (2015)
  • Author(s): 橋本亮太
  • Publisher: 中山書店
• [Book] 治療抵抗性統合失調症の治療戦略と病態研究-真の治療抵抗性統合失調症と見かけ上の治療抵抗性統合失調症 (2014)
  • Author(s): 橋本亮太、安田由華、山森英長、藤本美智子、武田雅俊、
  • Publisher: 臨床精神薬理、星和書店
• [Book] 精神医学的療法 (2014)
  • Author(s): 橋本亮太
  • Publisher: 痛みのマネジメントupdate-基礎知識から緩和ケアまで-、日本医師会雑誌特別号メジカルビュー社
• [Book] 今後期待される新しいメカニズムの向精神薬 (2014)
  • Author(s): 橋本亮太、山森英長、安田由華、大井一高、藤本美智子、梅田知美、武田雅俊、
  • Publisher: 臨床精神薬理、星和書店
• [Book] イメージングジェネティクスで精神疾患に迫る (2014)
  • Author(s): 橋本亮太、山森英長、安田由華、大井一高、藤本美智子、梅田知美、武田雅俊、
  • Publisher: Medical Scienece Digest、ニューサイエンス社
• [Book] 急性期から回復期の治療、統合失調症ケーススタディー-症例が導く社会復帰・QOL向上への道- (2014)
  • Author(s): 橋本亮太、山森英長、安田由華、大井一高、藤本美智子、武田雅俊、
  • Publisher: クロザピン100のQ＆A- 治療抵抗性への挑戦-、星和書店
• [Book] 大阪大学では前薬をある程度継続しながら導入するのですか？ (2014)
  • Author(s): 橋本亮太、山森英長、安田由華、藤本美智子、武田雅俊、
  • Publisher: クロザピン100のQ＆A- 治療抵抗性への挑戦-、星和書店
• [Book] 大阪大学での増量、減量方法のテクニックを教えてください (2014)
  • Author(s): 橋本亮太、山森英長、安田由華、藤本美智子、武田雅俊、
  • Publisher: クロザピン100のQ＆A- 治療抵抗性への挑戦-、星和書店
• [Remarks] 大阪大学大学院医学系研究科精神医学教室分子精神医学研究グループ
  • URL: http://www.sp-web.sakura.ne.jp/lab/index.html
• [Remarks] 分子精神医学研究グループ
  • URL: http://www.sp-web.sakura.ne.jp/lab/index.html
• [Patent(Industrial Property Rights)] 精神疾患判定装置、及び、精神疾患判定方法 (2014)
  • Inventor(s): 橋本亮太、三浦健一郎、藤本美智子
  • Industrial Property Rights Holder: 国立大学法人大阪大学
  • Industrial Property Rights Type: 特許
  • Industrial Property Number: 2014-182369
  • Filing Date: 2014-09-08