| Project/Area Number |
26670570
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Radiation science
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| Research Institution | Dokkyo Medical University (2015)
National Institute of Radiological Sciences (2014) |
|---|
Principal Investigator |
Kobashi Gen 獨協医科大学, 医学部, 教授 (60270782)
|
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| Co-Investigator(Kenkyū-buntansha) |
SAITO Toshiyuki 放射線医学総合研究所, 重粒子医科学センター, 研究員 (90205667)
|
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| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 膵がん / バイオマーカー / 遺伝子発現 / トランスクリプトーム / トランスクリプト―ム / 膵臓癌 / 診断マーカー / トランスクリプトーム解析 |
|---|
| Outline of Final Research Achievements |
To develop novel biomarkers useful for detecting and monitoring pancreas cancer, 17 cases and 4 control were obtained. A high accuracy large-scale gene expression analysis of 8919 mRNAs revealed difference of transcriptome between the cases and controls. It is suggested that studies focusing on differentially-expressed transcripts might discriminate cases from controls with high accuracy in the future.
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