| Project/Area Number |
26670639
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurosurgery
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| Research Institution | Gifu University |
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Principal Investigator |
SOEDA Akio 岐阜大学, 医学部附属病院, 助教 (20444276)
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| Co-Investigator(Kenkyū-buntansha) |
岩間 亨 岐阜大学, 大学院医学系研究科, 教授 (20303498)
高木 俊範 岐阜大学, 医学部附属病院, 助教 (00452152)
辻本 真範 岐阜大学, 大学院医学系研究科, 非常勤講師 (70509554)
山内 圭太 岐阜大学, 医学部附属病院, 医員 (10452153)
宮居 雅文 岐阜大学, 医学部附属病院, 医員 (60613502)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 悪性脳腫瘍 / IDH1変異 / IGFBP7 / COLA1 / 脳腫瘍幹細胞 |
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| Outline of Final Research Achievements |
The prognosis of malignant brain tumor depends on the presence or absence of IDH1 mutation. It is also known that malignant brain tumors contain cancer stem cells that are the source of tumors. We have showed that IGFBP 7 and COLA 1 are involved in malignant tumor diversity.
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