| Project/Area Number |
26670720
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Kyoto University |
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Principal Investigator |
Kondoh Eiji 京都大学, 医学(系)研究科(研究院), 講師 (10544950)
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| Co-Investigator(Kenkyū-buntansha) |
MOGAMI Haruta 京都大学, 大学院医学研究科, 助教 (40378766)
KONISHI Ikuo 京都大学, 大学院医学研究科, 教授 (90192062)
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| Co-Investigator(Renkei-kenkyūsha) |
SONE Masakatsu 京都大学, 大学院医学研究科, 講師 (40437207)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | ヒトiPS細胞 / 血管内皮細胞 / 不死化EVT / 妊娠高血圧症候群 / 母体子宮らせん動脈リモデリング不全 / iPS細胞 / リモデリング / 妊娠高血圧腎症 |
|---|
| Outline of Final Research Achievements |
Direct-contact co-culture of human induced pluripotent stem cell-derived endothelial cells adhered to immortalized extravillous trophoblast HTR-8/ SVneo cells decreased cell cell viability of human induced pluripotent stem cell-derived endothelial cells (79.7% versus 49.7%) as well as populations of CD144 positive cells.
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