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Establishment of iPS cells derived from keloid patients for the purpose of drug discovery

Research Project

Project/Area Number 26670778
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Plastic surgery
Research InstitutionJuntendo University

Principal Investigator

MIZUNO Hiroshi  順天堂大学, 医学部, 教授 (80343606)

Co-Investigator(Kenkyū-buntansha) 飛田 護邦  順天堂大学, 医学部, 非常勤講師 (10599038)
Research Collaborator OHSHITA Takashi  
TAJIMA Satoshi  
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywordsケロイド / iPS細胞 / 創薬
Outline of Final Research Achievements

The purpose of this study was to establish iPS cells from dermal derived fibroblasts of keloid patients and induce differentiation into keloid fibroblasts to investigate mechanisms of development and disease pathology of keloid.
Through this study, however, iPS cells were not established from keloid patient-derived fibroblasts, and as a result, establishment of a method to efficiently establish iPS cells from keloid fibroblasts and to differentiate into fibroblasts could not be established.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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