| Project/Area Number |
26670785
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Emergency medicine
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| Research Institution | Kyoto University |
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Principal Investigator |
KOIKE KAORU 京都大学, 医学(系)研究科(研究院), 教授 (10267164)
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| Co-Investigator(Kenkyū-buntansha) |
HIRAKAWA Keiko 日本医科大学, 医学部, 助教 (30165162)
SUZUKI Takao 京都大学, 医学(系)研究科(研究院), 講師 (40328810)
SATO Norio 京都大学, 医学(系)研究科(研究院), 講師 (30409205)
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| Co-Investigator(Renkei-kenkyūsha) |
MORIYAMA Tsuyoshi 東京工芸大学, 工学部, 准教授 (80449032)
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| Project Period (FY) |
2014-04-01 – 2015-03-31
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| Project Status |
Completed (Fiscal Year 2014)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2014: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | 近赤外分光法 / 敗血症 / ケモメトリクス / 複雑な混合物 / ケモメトリクス解析 |
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| Outline of Final Research Achievements |
Near infrared (NIR) spectroscopy is a noninvasive, contactless and real-time analytical technology that may yield a variety of promising bedside monitoring systems in the field of emergency and critical care medicine. Rats were injected 2 mg/kg or 10mg/kg of lipopolysaccharide (LPS) intraperitoneally and the plasma was collected. The present study revealed that our technique using NIR spectra could differentiate septic plasmas obtained from LPS 2 mg/kg group and 10mg/kg group. This technique proved to be a novel signal processing method that comprehensively handles the signal of electromagnetic waves derived from complex mixture.
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