Research Project
Grant-in-Aid for Challenging Exploratory Research
To determine the initial signaling from the cancer stem cells for the recurrence, we implanted the cancer tissues obtained by biopsy or surgery from the patient with oral cancer into immunodeficient NOG mice (NOD.Cg-Prkdcscid 112rgtmlSug/Jic). The grown secondary tumors were implanted into either normal or pre-irradiated site. We found activation of HIF-1 in pre-irradiated site and analyzed the gene expression profile in tumors implanted in normal or pre-irradiated site.
All 2016
All Presentation (1 results) (of which Invited: 1 results)