Molecular release for tissue engineering based on ultrafast Mie scattered light
| Project/Area Number |
26702019
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Partial Multi-year Fund |
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| Research Field |
Medical systems
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| Research Institution | Keio University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥15,470,000 (Direct Cost: ¥11,900,000、Indirect Cost: ¥3,570,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2016: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2014: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
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| Keywords | フェムト秒レーザー / ドラッグデリバリー / 生分解性ポリマー / レーザー医工学 / レーザー医療 |
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| Outline of Final Research Achievements |
Stimuli-responsible controlled release of molecules was investigated by using near-infrared light toward the realization of efficient scaffold in tissue engineering. The method investigated was based on the ultrafast phenomena of intense Mie scattered light. Fabrication of guest-molecule-embedded capsules, experimental demonstration of femtosecond laser pulse-triggered molecular release, investigation on biodegradability of the polymers, fabrication of 3D structures as well as demonstration of molecular release were carried out. In summary, demonstration of molecular release via multi-photon process of near-infrared light was achieved.
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Report
(5 results)
Research Products
(41 results)
