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The effect of ultrasound therapy on high dose radiation damage to the rat's skin

Research Project

Project/Area Number 26750177
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionHirosaki University

Principal Investigator

Koeda Shuhei  弘前大学, 保健学研究科, 助教 (00455734)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords被ばく / リハビリテーション / 超音波療法 / 被ばく医療 / 放射線皮膚障害 / 超音波治療
Outline of Final Research Achievements

Rehabilitation intervention for the skin, muscle and respiratory management were effective for patients exposed to high dose radiation. However, there are very few fundamental studies and reports about rehabilitation offered to patients suffering from radiation exposure. The purpose of this study is to determine the effect of the rehabilitation on high-dose radiation injuries. We received ultrasound therapy for the model rat, and investigated the range-of-motion (ROM) of dorsiflexion of the ankle joints and the histopathological findings of the soleus muscle and skin. As a result of experiment, a radiation dose of at least 30 Gy is required to develop an animal model of local radiation damage. And, as for the rehabilitation treatment, it was found that mild exercise therapy and physiotherapy were effective methods. In addition, it was found that the ultrasound therapy led to inhibits chronic inflammation and the prevention of the range of motion limitation.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (3 results)

All 2016 2014

All Presentation (3 results)

  • [Presentation] 放射線熱傷に対する超音波治療の効果に関する試験的検討2016

    • Author(s)
      小枝周平, 成田大一, 佐藤ちひろ, 澄川幸志
    • Organizer
      第50回日本作業療法学会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2016-09-09
    • Related Report
      2016 Annual Research Report
  • [Presentation] 高線量局所被ばくに対するリハビリテーション治療の有効性2016

    • Author(s)
      小枝周平、小山内隆生、成田大一
    • Organizer
      第4回作業療法学系大学院ゼミナール
    • Place of Presentation
      札幌市教育文化会館(北海道札幌市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] Effects of the rehabilitation on the skin damage and the range of motion of the rats with X-ray irradiated hind limbs.2014

    • Author(s)
      Koeda S, Narita H, Ito K, Ito K, Tsushima H
    • Organizer
      1st educational symposium on radiation and health by young scientists (ESRAH2014)
    • Place of Presentation
      ホテルニューキャッスル(青森県弘前市)
    • Year and Date
      2014-09-21 – 2014-09-22
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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