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Effect of non-invasive brain stimulation on motor learning in stroke patients and understanding the neural mechanisms

Research Project

Project/Area Number 26750208
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKyoto Tachibana University (2016)
Kio University (2015)
Yamato University (2014)

Principal Investigator

Nakano Hideki  京都橘大学, 健康科学部, 助教 (60605559)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywordsリハビリテーション / 脳卒中 / 非侵襲脳刺激法 / 経頭蓋直流電気刺激 / 脳波 / 安静時脳活動 / 運動制御 / 運動学習
Outline of Final Research Achievements

This study showed that beta rhythms in left sensorimotor area in resting state before performing the task are related to spatial control, and beta rhythms in left parietal area are involved with time control in the motor adaptation learning task. In addition, it was revealed that increased excitability in left sensorimotor areas in resting state before performing the task induced by transcranial Direct Current Stimulation improves spatial control. These results suggest that resting brain activity before performing the task associates with motor skill acquisition, and activation of resting brain activity improves motor skill acquisition.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (32 results)

All 2017 2016 2015 2014

All Journal Article (14 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 13 results,  Open Access: 9 results,  Acknowledgement Compliant: 1 results) Presentation (14 results) Book (4 results)

  • [Journal Article] 中高年女性の下肢むくみに対する足趾把持機能向上インソールの介入効果.2017

    • Author(s)
      村田 伸,安彦鉄平,中野英樹,阪本昌志,松尾 大,川口道生,須合洋次,松井宏彰.
    • Journal Title

      保健の科学.

      Volume: 印刷中

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationships among Floating Toes, Toe Functions, and Static/Dynamic Balance2017

    • Author(s)
      村田 伸,安彦鉄平,中野英樹,阪本昌志,松尾 大,川口道生.
    • Journal Title

      Japanese Journal of Health Promotion and Physical Therapy

      Volume: 6 Issue: 4 Pages: 165-169

    • DOI

      10.9759/hppt.6.165

    • NAID

      130006907495

    • ISSN
      2186-3741, 2187-3305
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of vibratory stimulation-induced kinesthetic illusions on the neural activities of patients with stroke2016

    • Author(s)
      Kodama T, Nakano H, Ohsugi H, Murata S
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 28 Issue: 2 Pages: 419-425

    • DOI

      10.1589/jpts.28.419

    • NAID

      130005127386

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Development of Insoles (Shoe Inserts) to Improve the Toe Grip Function2016

    • Author(s)
      村田 伸,安彦鉄平,中野英樹,阪本昌志,松尾 大,川口道生.
    • Journal Title

      Japanese Journal of Health Promotion and Physical Therapy

      Volume: 6 Issue: 3 Pages: 139-143

    • DOI

      10.9759/hppt.6.139

    • NAID

      130005432632

    • ISSN
      2186-3741, 2187-3305
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Improvement of Gait Function by Increasing the Contribution of Peripheral Sensation from the Ankle during Postural Control in a Patient with Stroke: A Case Report2016

    • Author(s)
      澳 昂佑,木村大輔,松木明好,井上純爾,服部暁穂,中野英樹,川原 勲.
    • Journal Title

      Rigakuryoho Kagaku

      Volume: 31 Issue: 2 Pages: 355-360

    • DOI

      10.1589/rika.31.355

    • NAID

      130005149320

    • ISSN
      1341-1667, 2434-2807
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of voluntary and automatic control of center of pressure sway during quiet standing.2015

    • Author(s)
      Ueta K, Okada Y, Nakano H, Osumi M, Morioka S.
    • Journal Title

      J Mot Behav.

      Volume: 47(3) Issue: 3 Pages: 256-264

    • DOI

      10.1080/00222895.2014.974496

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Effect of anticipation triggered by a prior dyspnea experience on brain activity2015

    • Author(s)
      Nakai H, Tsujimoto K, Fuchigami T, Ohmatsu S, Osumi M, Nakano H, Fukui M, Morioka S.
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 27 Issue: 3 Pages: 635-639

    • DOI

      10.1589/jpts.27.635

    • NAID

      130005061616

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 橈骨遠位端骨折術後患者に対する腱振動刺激による運動錯覚が急性疼痛に与える効果 - 手術後翌日からの早期介入 -2015

    • Author(s)
      今井亮太,大住倫弘,平川善之,中野英樹,福本貴彦,森岡 周
    • Journal Title

      理学療法学

      Volume: 42(1) Pages: 1-7

    • NAID

      110009912784

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 脳機能回復と認知神経的アプローチ2015

    • Author(s)
      中野英樹
    • Journal Title

      理学療法ジャーナル

      Volume: 49(9) Pages: 813-819

    • Related Report
      2015 Research-status Report
  • [Journal Article] Brain Activity Associated with the Illusion of Motion Evoked by Different Vibration Stimulation Devices: An fNIRS Study2014

    • Author(s)
      Imai R, Hayashida K, Nakano H, Morioka S
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 26 Issue: 7 Pages: 1115-1119

    • DOI

      10.1589/jpts.26.1115

    • NAID

      130004677698

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Activation of the serotonergic system by pedaling exercise changes anterior cingulate cortex activity and improves negative emotion2014

    • Author(s)
      Ohmatsu S, Nakano H, Tominaga T, Terakawa Y, Murata T, Morioka S
    • Journal Title

      Behav Brain Res

      Volume: 270 Pages: 112-117

    • DOI

      10.1016/j.bbr.2014.04.017

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] entral neural mechanisms of interindividual difference in discomfort during sensorimotor incongruence in healthy volunteers: an experimental study2014

    • Author(s)
      Nishigami T, Nakano H, Osumi M, Tsujishita M, Mibu A, Ushida T
    • Journal Title

      Rheumatology (Oxford)

      Volume: 印刷中 Issue: 7 Pages: 1194-1199

    • DOI

      10.1093/rheumatology/ket494

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] actors associated with the modulation of pain by visual distortion of body size2014

    • Author(s)
      Osumi M, Imai R, Ueta K, Nakano H, Nobusako S, Morioka S
    • Journal Title

      Front Hum Neurosci

      Volume: 8 Pages: 00137-00137

    • DOI

      10.3389/fnhum.2014.00137

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 振動刺激による運動錯覚時の脳内神経活動および機能的関連2014

    • Author(s)
      兒玉隆之,中野英樹,大住倫弘,森岡 周,大杉紘徳,安彦鉄平
    • Journal Title

      理学療法学

      Volume: 41(2) Pages: 43-51

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] 適応的運動学習における安静時脳活動は時間・空間的制御に関連する.2017

    • Author(s)
      山本浩人,中野英樹,石垣智也,森岡 周.
    • Organizer
      第52回日本理学療法学術大会.
    • Place of Presentation
      幕張メッセ国際会議場
    • Year and Date
      2017-05-12
    • Related Report
      2016 Annual Research Report
  • [Presentation] 運動イメージ時の脳波周波数パターンは両側同期性に出現する 脳波周波数パターンセンシングシステムを用いたBCIの創出を目指して.2016

    • Author(s)
      兒玉隆之,中野英樹,大杉紘徳,村田 伸,高間良介.
    • Organizer
      第51回日本理学療法学術大会.
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2016-05-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] 足趾把持機能を高めるインソールが健常者の足趾機能ならびに静的・動的バランスに及ぼす効果 ランダム化比較試験.2016

    • Author(s)
      中野英樹,村田 伸,安彦鉄平,阪本昌志,松尾 大,川口道生,須合洋次, 松井宏彰.
    • Organizer
      第6回日本ヘルスプロモーション理学療法学会学術集会.
    • Place of Presentation
      県立広島大学
    • Related Report
      2016 Annual Research Report
  • [Presentation] 視覚運動学習課題における時間的・空間的制御に関連する安静時脳活動の検討ーPower spectrum解析を用いてー.2016

    • Author(s)
      山本浩人,中野英樹,森岡 周.
    • Organizer
      第2回身体運動制御学とニューロリハビリテーション研究会.
    • Place of Presentation
      畿央大学
    • Related Report
      2016 Annual Research Report
  • [Presentation] Readiness potentials of self-generated gait initiation2014

    • Author(s)
      Waki S, Nakano H, Morioka S
    • Organizer
      48th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      Washington DC (United States of America)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Research-status Report
  • [Presentation] Effect of anticipation triggered by prior dyspnea experience on brain activity2014

    • Author(s)
      Nakai H, Tsujimoto K, Fuchigami T, Omatsu S, Nakano H, Morioka S
    • Organizer
      48th Annual Meeting of Society for Neuroscience
    • Place of Presentation
      Washington DC (United States of America)
    • Year and Date
      2014-11-15 – 2014-11-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 振動刺激による運動錯覚惹起までの脳神経活動に関する時間的解析の試み―Microstate segmentation 解析を用いて―2014

    • Author(s)
      兒玉隆之,中野英樹,大住倫弘,森岡 周,谷本正智,大杉紘徳,安彦鉄平
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 過去の呼吸経験により形成された予測情報がその後の呼吸困難感に及ぼす影響2014

    • Author(s)
      中井秀樹,渕上 健,大松聡子,中野英樹,森岡 周
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 運動視刺激を用いたボトムアップおよびトップダウン的注意喚起が脳波活動に及ぼす影響2014

    • Author(s)
      辻本憲吾,中野英樹,大住倫弘,森岡 周
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 視覚的身体像に対する不快情動が疼痛閾値に与える影響―ラバーハンド錯覚を用いて―2014

    • Author(s)
      大住倫弘,今井亮太,中野英樹,森岡 周
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 身体と関連した動詞提示における意味プライミングと運動の準備についての検討―脳波を用いて―2014

    • Author(s)
      宮﨑有希,冨永孝紀,大住倫弘,中野英樹,森岡 周
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 道具把持画像による心的回転課題は反応時間を遅延させ上側頭溝と下前頭回を賦活させるEEG 研究2014

    • Author(s)
      平田康介,中野英樹,石垣智也,森岡 周
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 認知課題付加が脳卒中片麻痺者の静止立位時の COP 動揺と下腿筋同時活動に与える影響2014

    • Author(s)
      植田耕造,菊地 萌,坂元 諒,大住倫弘,中野英樹,向井公一,矢田定明,森岡 周
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Presentation] 跨ぎ動作による障害物回避計画時の脳活動2014

    • Author(s)
      藤原菜津,植田耕造,石垣智也,菅沼惇一,脇 聡子,中野英樹,森岡 周
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-05-30 – 2014-06-01
    • Related Report
      2014 Research-status Report
  • [Book] Understanding neural mechanisms of action observation and execution in motor skill learning using electroencephalography. Electroencephalography.2017

    • Author(s)
      Nakano H, Kodama T.
    • Publisher
      InTech.
    • Related Report
      2016 Annual Research Report
  • [Book] Motor imagery and action observation as effective tools for physical therapy. Neurological Physical Therapy.2017

    • Author(s)
      Nakano H, Kodama T.
    • Publisher
      InTech.
    • Related Report
      2016 Annual Research Report
  • [Book] Neuroscience-based rehabilitation for stroke patients. Neurological Physical Therapy.2017

    • Author(s)
      Kodama T, Nakano H
    • Publisher
      InTech.
    • Related Report
      2016 Annual Research Report
  • [Book] 脳卒中理学療法ベスト・プラクティス2014

    • Author(s)
      中野英樹,森岡 周
    • Total Pages
      288
    • Publisher
      文光堂
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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