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Development of pump-integrated separation medium for on-site analysis

Research Project

Project/Area Number 26790033
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Nano/Microsystems
Research InstitutionKyoto University

Principal Investigator

Naito Toyohiro  京都大学, 工学(系)研究科(研究院), 助教 (10711806)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords電気浸透ポンプ / マイクロ・ナノデバイス / オンサイト分析
Outline of Final Research Achievements

The main stream of the studies related to LC has been pursuance of high separation performance. On the other hand, the demand for an on-site analysis has been increased recently, One of the ways to develop on-site LC device is employing an electroosmotic pump (EOP).
We developed novel separation medium based on microfabricated structure and monolithic materials, which have pumping function and separation performance. The sulfonate-modified monolithic material generated 73.5 kPa, which was 20 kPa higher than that of the non-treated silica monolithic materials. To evaluate the effect of the internal microstructure on discharged pressure. Packing ratio of the structures in the channel and length of the long side of structure were controlled. Discharged pressure of EOP was proportional to the packing ratio of microstructure. Length of the of the microstructure was also related to pressure discharge.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (11 results)

All 2015 2014

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (10 results) (of which Int'l Joint Research: 5 results,  Invited: 2 results)

  • [Journal Article] : Hydrodynamic Nonadhesive Cell Retaining in a Microfluidic Circuit for Stress-less Suspension Culture2015

    • Author(s)
      Naito, T.; Kaji, N.; Tokeshi, M.; Kubo, T.; Baba, Y.; Otsuka, K.
    • Journal Title

      Anal. Methods 2015

      Volume: in press

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Development of electroosmotic pumps based on materials for LC columns2015

    • Author(s)
      Toyohiro Naito, Akihiro Kunisawa, Shunta Futagami, Takuya Kubo, Koji Otsuka
    • Organizer
      2015 International Chemical Congress of Pacific Basin Societies (Pacifichem 2015)
    • Place of Presentation
      Honolulu, HI, USA
    • Year and Date
      2015-12-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Electroosmotic Pump Based on Separation Media for Miniaturized LC Device2015

    • Author(s)
      Toyohiro Naito, Akihiro Kunisawa, Shunta Futagami, Takuya Kubo, Koji Otsuka
    • Organizer
      19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (mTAS 2015)
    • Place of Presentation
      Gyeongju, Korea
    • Year and Date
      2015-10-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Evaluation of Column Performance of Microfabricated 3D Structures for LC Separations2015

    • Author(s)
      Makoto Nakamura*, Toyohiro Naito, Takuya Kubo, Koji Otsuka
    • Organizer
      19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (mTAS 2015)
    • Place of Presentation
      Gyeongju, Korea
    • Year and Date
      2015-10-25
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chemical and Structural Improvement of a Electroosmotic Flow Pump2015

    • Author(s)
      Toyohiro Naito, Akihiro Kunisawa, Shunta Futagami, Takuya Kubo, Koji Otsuka
    • Organizer
      7th International Symposium on Microchemistry and Microsystems (ISMM2015)
    • Place of Presentation
      Kyoto Univ. Katsura, Kyoto, Japan
    • Year and Date
      2015-06-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Evaluation of the Kinetic Performance of Micro-fabricated 3D Structures for LC Columns2015

    • Author(s)
      Makoto Nakamura, Toyohiro Naito, Takuya Kubo, Koji Otsuka
    • Organizer
      7th International Symposium on Microchemistry and Microsystems (ISMM2015)
    • Place of Presentation
      Kyoto Univ. Katsura, Kyoto, Japan
    • Year and Date
      2015-06-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of Miniaturized LC Columns Concerning On-Site Analysis2015

    • Author(s)
      Toyohiro Naito*, Akihiro Kunisawa, Shunta Futagami, Takuya Kubo, Koji Otsuka
    • Organizer
      PITTCON 2015
    • Place of Presentation
      New Orleans, LO, USA
    • Year and Date
      2015-03-08 – 2015-03-12
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Fabrication of 3D Micro Fractal Structures for a Liquid Chromatography Device2014

    • Author(s)
      Makoto Nakamura*, Toyohiro Naito, Takuya Kubo, Koji Otsuka
    • Organizer
      18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (mTAS2014)
    • Place of Presentation
      San Antonio, TX, USA
    • Year and Date
      2014-10-26 – 2014-10-30
    • Related Report
      2014 Research-status Report
  • [Presentation] A three dimensional fabrication by standard soft lithography equipment2014

    • Author(s)
      Toyohiro Naito*, Takuya Kubo, Takao Yasui, Noritada Kaji, Yoshinobu Baba, Koji Otsuka
    • Organizer
      6th International Symposium on Microchemistry and Microsystems (ISMM2014)
    • Place of Presentation
      Singapore
    • Year and Date
      2014-07-30 – 2014-08-01
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Fabrication and Investigation of Pillar Array Columns Made of SU-82014

    • Author(s)
      Shunta Futagami*, Toyohiro Naito, Takuya Kubo, Koji Otsuka
    • Organizer
      41st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC2014 New Orleans)
    • Place of Presentation
      New Orleans, LO, USA
    • Year and Date
      2014-05-11 – 2014-05-15
    • Related Report
      2014 Research-status Report
  • [Presentation] Fundamental Investigations of Monolithic Materials for a Portable LC Device Applicable to an On-site Analysis2014

    • Author(s)
      Akihiro Kunisawa*, Toyohiro Naito, Takuya Kubo, Koji Otsuka
    • Organizer
      41st International Symposium on High Performance Liquid Phase Separations and Related Techniques (HPLC2014 New Orleans)
    • Place of Presentation
      New Orleans, LO, USA
    • Year and Date
      2014-05-11 – 2014-05-15
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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