Olfactory sensitivities in fasted and fed mice
| Project/Area Number |
26850061
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Applied biochemistry
|
|---|
| Research Institution | The University of Tokyo |
|---|
Principal Investigator |
Horio Nao 東京大学, 大学院農学生命科学研究科(農学部), 特任研究員 (80726448)
|
|---|
| Project Period (FY) |
2014-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Keywords | 嗅覚 |
|---|
| Outline of Final Research Achievements |
From our experience, it is known that food odor increases our appetite when we are hungry. Olfactory sensitivities in fasted and fed state may be different, however little is known about the role of olfactory sensory neurons in the modulation of olfactory sensitivities by huger state in mammals. Therefore we did the behavioral experiment and the olfactory bulb imaging which reflected activated odorant receptors in the olfactory sensory neurons. We revealed that olfactory sensitivities in fasted mice to some odor were significantly increased than those in fed mice and the threshold to the odorant in fasted mice and fed mice by olfactory imaging were similar. The olfactory sensitivities may be modulated not in olfactory sensory neurons but in higher brain.
|
Report
(4 results)
Research Products
(12 results)
-
[Journal Article] Ligand specificity and evolution of mammalian musk odor receptors: the effect of single receptor deletion on odor detection2016
Author(s)
Sato-Akuhara, N., Horio, N., Kato-Namba, A., Yoshikawa, K., Niimura, Y., Ihara, S., Shirasu, M.*, and Touhara, K.*
-
Journal Title
The Journal of Neuroscience
Volume: 36
Issue: 16
Pages: 4482-4491
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
-
-
-
-
-
-
-
-
-
-
-
