Characterization of antigen sampling cells in gill epithelium of fish
| Project/Area Number |
26850128
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Aquatic bioproduction science
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| Research Institution | Tokyo University of Marine Science and Technology (2015)
Fisheries Research Agency (2014) |
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Principal Investigator |
KATO GOSHI 東京海洋大学, その他部局等, 助教 (50624219)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 抗原取り込み / 鰓粘膜 / Aeromonas salmonicida / UEA-1 / 浸漬ワクチン / 次世代シークエンサー / フローサイトメトリー / 魚類免疫 / Vibrio anguillarum / Yersinia ruckeri / UEA1 |
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| Outline of Final Research Achievements |
Bath-vaccination is a useful method to immunize small fish that injected vaccine is not suitable for. However, this method can be used for limited number of fish diseases. Vaccine antigens bath-vaccinated to fish are taken up by gill epithelial antigen sampling (GAS) cells. In this study, we revealed that GAS cell take up only bacterins which shows protective efficacy as bath-vaccine. Understanding a physiology of the GAS cells may contribute to expansion of the usage of bath-vaccination method.
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Report
(3 results)
Research Products
(8 results)
