Develepment of catalyst-controled chemoselective reactions
| Project/Area Number |
26860012
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical pharmacy
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| Research Institution | Kyushu University |
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Principal Investigator |
Yazaki Ryo 九州大学, 薬学研究科(研究院), 助教 (70635812)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | 化学選択性 / 位置選択性 / アミノアルコール / アミノジオール / 協奏機能触媒 / 官能基導入 / 無保護 / アトムエコノミー / 共役付加反応 / 触媒 |
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| Outline of Final Research Achievements |
Catalytic hydroxy group-selective conjugate addition reactions of amino alcohols were developed. A variety of functional groups such as azide group installation for click-chemistry and facile fluorescent labeling onto the less reactive hydroxy group demonstrated the synthetic utility of the present chemoselective catalysis. Moreover, chemo- and regioselective reaction of unprotected aminodiol was achieve.
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Report
(3 results)
Research Products
(18 results)
