Brain activity of postoperative cognivite disorder: fMRI study
Project/Area Number |
26861243
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Anesthesiology
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Research Institution | Wakayama Medical University |
Principal Investigator |
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
Keywords | 術後認知機能障害 / 安静時機能的結合 / 術後認知機能障害と安静時機能的結合 / 術後慢性疼痛 / 機能的MRI |
Outline of Final Research Achievements |
Seed-based correlation analysis from Default Mode Network (DMN) was proceeded. Functional connectivity from DMN was calculated, and functional connectivity was comparered between postoperative cognitive disorder group and healty control group using 2-sample t-test. Next, correlation analysis was performed between length of functional connectivity and clinical parameters (i.e. dulation of postopetative cognitive disorder or severity of disease). Significant difference was not detected among functional connectivity between postoperative cognitive disorder group and healthy control group. Singificant correlation was not observed between functinoal connectivity and clinical parameters at multiple comparison threshold (FWE corrected). However, a positive tendency of correlation was detected before applying multiple comparison.
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Report
(4 results)
Research Products
(2 results)