Establishment of objective and quantitative therapeutic evaluation method for transcorneal electrical stimulation therapy
| Project/Area Number |
26861439
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 経角膜電気刺激治療 / 外傷性視神経症 / 虚血性視神経症 / RAPDx / 瞳孔記録計RAPDｘ |
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| Outline of Final Research Achievements |
Using RAPDx for refractory optic nerve disease, objective and quantitative therapeutic evaluation of transcorneal electrical stimulation therapy (TES) was performed. The subjects were 5 cases of traumatic optic neuropathy and 9 cases of ischemic optic neuropathy. The amplitude score (AS) and latency score (LS) of RAPDx were measured before treatment and one month after the end of treatment, and statistical analysis was performed using t test for both groups AS and LS before and after treatment. The results showed that there was no statistically significant difference between AS and LS before and after treatment in both groups. For each case, there was one case with traumatic optic nerve cases and two cases with ischemic optic neuropathy in which AS was clearly reduced. It is suggested that TES may be effective even in a few cases, even in objective evaluation.
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Report
(5 results)
Research Products
(15 results)
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[Journal Article] Clinicopathological features in anterior visual pathway in neuromyelitis optica2016
Author(s)
Hokari M, Yokoseki A, Arakawa M, Saji E, Yanagawa K, Yanagimura F, Toyoshima Y, Okamoto K, Ueki S, Hatase T, Ohashi R, Fukuchi T, Akazawa K, Yamada M, Kakita A, Takahashi H, Nishizawa M, Kawachi I.
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Journal Title
Annals of Neurology
Volume: 79
Issue: 4
Pages: 605-624
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Presentation] 小児の甲状腺眼症の２症例2014
Author(s)
畑瀬哲尚、植木智志、羽入貴子、福地健郎
Organizer
第52回日本神経眼科学会
Place of Presentation
幕張メッセ（千葉県・千葉市）
Year and Date
2014-12-12 – 2014-12-13
Related Report
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