Mechanism analysis, suppresion of EAON by DC Transfected with PU.1.
Project/Area Number |
26861471
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Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Ophthalmology
|
Research Institution | Tokyo Medical University |
Principal Investigator |
|
Research Collaborator |
Umazume Akihiko 東京医科大学, 医学部, 助教 (20617568)
Yamakawa Naoyuki 東京医科大学, 医学部, 助教 (80599134)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | PU.1 / EAE / EAON / EAU / 視神経炎 / 遺伝子治療 / pu.1 |
Outline of Final Research Achievements |
In this study, we investigated PU.1 expression in the retina of mice with experimental autoimmune uveoretinitis (EAU) and the association between PU.1 expression level and inflammation in EAU. PU.1 may play crucial roles in the development and progression of inflammation in EAU
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Report
(4 results)
Research Products
(1 results)