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Clinical application of the bone graft method using the mesenchyma system stem cell derived from fat

Research Project

Project/Area Number 26861492
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Plastic surgery
Research InstitutionChiba University

Principal Investigator

KIRA Tomoe  千葉大学, 医学部附属病院, 医員 (80714146)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords再生医療 / 脂肪由来間葉系幹細胞 / 顎骨延長 / ADSC / 下顎骨延長 / 骨再生
Outline of Final Research Achievements

we made the experiment system that assumed a small animal a model on making the clinical trial for the purpose of shortening consolidation period of the human jawbone extension case and inspected the bone reproduction addition effect using the fat origin mesenchyma system stem cell. We understood that bone instruction group might promote a bone reproduction by the evaluation in one month after cell transplant. In addition, it was shown that the transplant cell was more likely to participate in bone reproduction in a transplant part without metabolism being absorbed because it was able to accept local existence of CD90,105 each which was an antigen of ADSC by the special stain.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (1 results)

All 2015

All Presentation (1 results)

  • [Presentation] ウサギ顎骨骨延長モデルにおける脂肪由来間葉系幹細胞による骨再生付加効果の検討2015

    • Author(s)
      吉良智恵
    • Organizer
      第23回日本形成外科学会基礎学術集会
    • Place of Presentation
      岩手県盛岡市盛岡県民会館
    • Year and Date
      2015-10-09
    • Related Report
      2015 Annual Research Report

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Published: 2014-04-04   Modified: 2017-05-10  

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