Ions and neutralization of carious inhibition in bio-active-glass

• Project/Area Number: 26861587
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Conservative dentistry
• Research Institution: Hokkaido University
• Principal Investigator: Kakuda Shinichi 北海道大学, 歯学研究科, 助教 (70707025)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000); Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
• Keywords: バイオアクティブグラス / う蝕予防 / シーラント材 / 中和作用 / SEM / フッ素 / カルシウム / イオン / グラスアイオノマーセメント / バイオアクティビティ / 酸性度 / う蝕抑制 / 脱灰 / 再石灰化 / Ｓ－ＰＲＧフィラー / 中和反応

Outline of Final Research Achievements

A phenomenon of tooth dissolution was not inhibited by the amount of fluoride. At the same time, the factor of acidity among the surrounding environment of the tooth was considered to be affected by the amount of the tooth's dissolution.
Caries prevention using pit and fissure sealant is a standard procedure in dental textbooks. It is thought that it becomes important information for the dentist who is involved in preventive dentistry to understand the characteristic of each material more deeply by comparing about the commercially available material.

Research Products

• [Int'l Joint Research] University of London(英国)
• [Int'l Joint Research] ブリティッシュコロンビア大学(カナダ)
• [Journal Article] Bond performance of “Touch and Cure” adhesives on resin core systems (2016)
  • Author(s): Kadowaki Y, Kakuda S, Kawano S, Katsumata A, Ting S, Hoshika S, Ikeda T, Tanaka T, Carvalho RM, Sano H.
  • Journal Title: Dental Materials Journal Volume: 35 Issue: 3 Pages: 386-391
  • DOI: 10.4012/dmj.2015-330
  • NAID: 130005155186
  • ISSN: 0287-4547, 1881-1361
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The effect of dentine surface preparation and reduced application time of adhesive on bonding strength (2016)
  • Author(s): Saikaew P, Chowdhury AF, Fukuyama M, Kakuda S, Carvalho RM, Sano H.
  • Journal Title: J Dent. Volume: 47 Pages: 63-70
  • DOI: 10.1016/j.jdent.2016.02.001
  • NAID: 120006024336
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Buffering or non-buffering; an action of pit-and-fissure sealants. (2015)
  • Author(s): Kakuda S, Sidhu SK, Sano H.
  • Journal Title: Journal of Dentistry Volume: 43 Issue: 10 Pages: 1285-1289
  • DOI: 10.1016/j.jdent.2015.06.013
  • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
• [Presentation] Fluoride releasing and recharging of glass-ionomer in contemporary restorative-material (2015)
  • Author(s): S. Kakuda, S. Hoshika, Y. Kadowaki, N. Fukuzawa, S. Kawano, S. Ting, A. Katsumata, A. Chowdhury, P. Saikaew, J. Sun, E. Seitoku, K. Okuyama, C. Kawamoto, T. Ikeda, T. Tanaka, D. Selimovic, R. Carvalho, H. Sano
  • Organizer: the 47th Meeting of CED-IADR
  • Place of Presentation: トルコ共和国アンタルヤ
  • Year and Date: 2015-10-15
  • Int'l Joint Research
• [Presentation] Microtensile Bond Strength of a Universal Adhesive with Different Application Protocols (2015)
  • Author(s): Saikaew P, Chowdhury AFM A, Kawano S, Kakuda S, Sano H
  • Organizer: The 6th International Congress on Adhesive Dentistry
  • Place of Presentation: バンコク（タイ）
  • Year and Date: 2015-01-31 – 2015-02-01
• [Presentation] Bonding Efficacy of a Universal Adhesive in Different Etching Methods (2015)
  • Author(s): Chowdhury AFM A, Saikaew P, Ting S, Kawano S, Fukuzawa N, Kakuda S, Sano H
  • Organizer: The 6th International Congress on Adhesive Dentistry
  • Place of Presentation: バンコク（タイ）
  • Year and Date: 2015-01-31 – 2015-02-01
• [Presentation] Viscosity Effect of Adhesive System on Resin-Dentin Microtensile Bond Strength (2015)
  • Author(s): Seitoku E, Sun JH, Abe S, Hoshika S, Kakuda S, Yoshida Y, Sano H
  • Organizer: The 6th International Congress on Adhesive Dentistry
  • Place of Presentation: バンコク（タイ）
  • Year and Date: 2015-01-31 – 2015-02-01
• [Presentation] Micro-tensile Bond Strength of 1-step and 2-step Adhesive to Human and Bovine Coronal Dentin (2015)
  • Author(s): Sun JH, Seitoku E, Kakuda S, Hoshika S, Sano H
  • Organizer: The 6th International Congress on Adhesive Dentistry
  • Place of Presentation: バンコク（タイ）
  • Year and Date: 2015-01-31 – 2015-02-01
• [Presentation] Neutralization-Property of Conservative Pits and Fissure Sealant (2014)
  • Author(s): Shinichi KAKUDA, Shuhei HOSHIKA, Yasuhiro YOSHIDA and Hidehiko SANO
  • Organizer: Congress of International Association for Dental Research / Pan European Region
  • Place of Presentation: ドゥブロブニク（クロアチア）
  • Year and Date: 2014-09-08 – 2014-09-15