| Project/Area Number |
26861615
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Conservative dentistry
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| Research Institution | Fukuoka Dental College |
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Principal Investigator |
FUJIMOTO Akie 福岡歯科大学, 口腔歯学部, 助教 (60707983)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | プロバイオティクス / う蝕菌原因菌 / 齲蝕病原細菌 / う蝕原因菌 |
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| Outline of Final Research Achievements |
Lactobacillus salivarius WB21 (WB 21) has been reported to improve periodontal disease and halitosis. In this study, the effect of WB 21 on the caries-causing microorganism Streptococcus mutans (Sm) was investigated to further confirm the effect of the oral use of lactic acid bacteria.In mixed culture experiments, it was found that WB21 suppressed Sm growth. In addition, it was found that the addition of WB21 reduced the amount of insoluble glucan produced by Sm.
The results of the present study suggested that WB21 did not increase the risk of dental caries and that it may even have a caries suppression effect.
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