Role of Androgen Receptor in Breast Cancer
Project/Area Number |
26870597
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Tumor diagnostics
Tumor therapeutics
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Research Institution | Tokai University |
Principal Investigator |
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Project Period (FY) |
2014-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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Keywords | 乳癌 / アンドロゲンレセプター / トリプルネガティブ / エストロゲンレセプター |
Outline of Final Research Achievements |
Our study investigate compare the frequency of Androgen receptor (AR) expression in Estrogen Receptor (ER), PgR, ki-67 and subgroups and compare survival in tumor with high expression of AR and low expression in each subgroup to use microarray database. Our data showed AR was significantly positive correlation ER. AR high expression is good prognostic factor in ER positive breast cancer. However AR high expression is poor prognostic factor in Triple negative breast cancer.
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Report
(3 results)
Research Products
(9 results)
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[Journal Article] Prognostic factors of HER2-positive breast cancer patients who develop brain metastasis: a multicenter retrospective analysis.2015
Author(s)
Hayashi N, Niikura N, Masuda N, Takashima S, Nakamura R, Watanabe K, Kanbayashi C, Ishida M, Hozumi Y, Tsuneizumi M, Kondo N, Naito Y, Honda Y, Matsui A, Fujisawa T, Oshitanai R, Yasojima H, Yamauchi H, Saji S, Iwata H.
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Journal Title
Breast Cancer Res Treat
Volume: 149(1)
Issue: 1
Pages: 277-84
DOI
Related Report
Peer Reviewed
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[Journal Article] Clinical characteristics and outcome of bone-only metastasis in inflammatory and noninflammatory breast cancers.2015
Author(s)
Kai M, Kogawa T, Liu DD, Fouad TM, Kai K, Niikura N, Hsu L, Willey JS, Theriault RL, Valero V, Ueno NT.
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Journal Title
Clin Breast Cancer
Volume: 15(1)
Issue: 1
Pages: 37-42
DOI
Related Report
Peer Reviewed
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[Journal Article] Treatment outcomes and prognostic factors for patients with brain metastases from breast cancer of each subtype: a multicenter retrospective analysis.2014
Author(s)
Niikura N, Hayashi N, Masuda N, Takashima S, Nakamura R, Watanabe K, Kanbayashi C, Ishida M, Hozumi Y, Tsuneizumi M, Kondo N, Naito Y, Honda Y, Matsui A, Fujisawa T, Oshitanai R, Yasojima H, Tokuda Y, Saji S, Iwata H.
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Journal Title
Breast Cancer Res Treat
Volume: 147(1)
Issue: 1
Pages: 103-12
DOI
Related Report
Peer Reviewed
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