Effect of exercise adn phsical activity on blood myokine and adipokines concentration in elderly with heart diseases

Research Project

Project/Area Number	26870702
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Multi-year Fund
Research Field	Rehabilitation science/Welfare engineering Applied health science
Research Institution	Kyoto Pharmaceutical University
Principal Investigator	Numao Shigeharu 京都薬科大学, 薬学部, 講師 (90454074)
Project Period (FY)	2014-04-01 – 2018-03-31
Project Status	Completed (Fiscal Year 2017)
Budget Amount *help	¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000) Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000) Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000) Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords	アディポネクチン / イリシン / 脳性ナトリウム利尿ペプチド / 高密度リポタンパク質コレステロール / 高齢心疾患患者 / マイオカイン / アディポカイン / 心疾患 / 運動療法 / 身体活動量 / 運動教室
Outline of Final Research Achievements	This study was to determine the effects of exercise therapy and physical activity on blood myokine, adipokines, and physiological functions (cardiovascular function and cardiovascular diseases risk factors in elderly with heart diseases using cross-sectional and longitudinal design. Despite presence or absence of exercise therapy participation, change in blood myokine, adipokines, and physiological functions did not differ for 3 year.However, daily physical activity, especially spent-time of moderate-vigorous physical activity was associated with brain natriuretic peptide and high density lipoprotein cholesterol.