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Study on Endotoxin Concentration in House Dust and Allergy Symptoms

Research Project

Project/Area Number 26870871
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeMulti-year Fund
Research Field Environmental risk control and evaluation
Architectural environment/Equipment
Research InstitutionNational Institute of Public Health

Principal Investigator

KIM Hoon  国立保健医療科学院, その他部局等, 主任研究官 (00454033)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsエンドトキシン / アレルギー / ハウスダスト / 住宅 / 室内環境
Outline of Final Research Achievements

Endotoxin (ET) has been ascribed as allergen on the hygiene hypothesis (Strachan DP, 1989). Medium-term goal of this study is to ascertain the effect of endotoxin on allergic occupants. 67 detached houses were investigated by conducting questionnaire, collecting house dust and sampling indoor air.
As a result, ET concentrations (CET) in house dust were determined in a wide range from about 250 to 35,000EU/g (mean 7,405±6,885), and showed several thousand EU/g as the typical value. Significant correlation between allergic symptoms and CET was not observed statistically, and bronchial problems like asthma produced the same result. Meanwhile, allergic individuals were likely to be more at the houses with lower CET, and it was thought to be causally related to family members’ recognition and efforts to improve the indoor environment by cleaning and ventilating etc. A seasonal difference of CET was observed as showing those in summer and interim season were higher than in winter.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (3 results)

All 2016 2015

All Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] エンドトキシンの室内環境濃度2016

    • Author(s)
      金勲、柳宇、鍵直樹、東賢一、Lim Eunsu、大澤元毅、林基哉
    • Organizer
      日本建築学会学術大会2016
    • Place of Presentation
      福岡
    • Year and Date
      2016-09-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] Endotoxin Concentration in House Dust and Indoor Air in Japan2016

    • Author(s)
      Hoon KIM, Eunsu LIM, U YANAGI, Naoki KAGI, Kenichi AZUMA, Haruki OSAWA and Motoya HAYASHI
    • Organizer
      Indoor Air 2016
    • Place of Presentation
      ベルギー
    • Year and Date
      2016-07-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] エンドトキシンの室内環境濃度2015

    • Author(s)
      金勲、Lim Eunsu、柳宇、鍵直樹、東賢一、大澤元毅、林基哉
    • Organizer
      室内環境学会学術大会(平成27年)
    • Place of Presentation
      沖縄
    • Year and Date
      2015-12-03
    • Related Report
      2015 Annual Research Report

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Published: 2014-04-04   Modified: 2017-05-10  

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