| Project/Area Number |
26885079
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Experimental psychology
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| Research Institution | Keio University |
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Principal Investigator |
Kosaki Yutaka 慶應義塾大学, 先導研究センター, 研究員 (80738469)
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | 道具的学習 / 目的的行動 / S-R習慣 / 連合過程 / 前帯状皮質 / 損傷 / 随伴性低下 / 強化子低価値化 / ラット / 習慣 / 時間 |
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| Outline of Final Research Achievements |
Instrumental behaviour of animals, including humans, is theorised to be mediated by two distinct processes. One is a process where a stimulus-response (S-R) association reinforced by the outcome of the response. The other is a goal-directed process, in which animals are sensitive to the contingency between response and its outcome as well as to the expected value of the outcome. In the current study, I examined the contribution of the peri-genual anterior cingulate cortex (ACC) to these distinct processes underlying instrumental behaviour. Using the contingency-degradation procedure and the outcome devaluation procedure, I found that the rats with ibotenic acid-induced lesions of the ACC performed comparably to the sham-lesioned control animals, in either of these tests. The results suggest that the peri-genual ACC, in contrast to the more anterior prelimbic cortex, is not crucial for the goal-directed control of instrumental behaviour.
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