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Establishment of bone regeneration unit increased by factors affecting bone formation for vertical bone augmentation

Research Project

Project/Area Number 26893075
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeSingle-year Grants
Research Field Dental engineering/Regenerative dentistry
Research InstitutionTokyo Medical and Dental University

Principal Investigator

Akino Norio  東京医科歯科大学, 歯学部附属病院, 医員 (10736002)

Co-Investigator(Kenkyū-buntansha) Kasugai Shohei  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (70161049)
Project Period (FY) 2014-08-29 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords非焼成ハイドロキシアパタイト粒子(U-HA) / ポリ-DL-乳酸(PDLLA) / 非結晶性ポリマー / 垂直的骨造成 / Ⅰ型・Ⅲ型コラーゲン / 骨補填材 / オンレーグラフト法 / 細胞凝集 / 1型・3型コラーゲン / 細胞凝集促進 / 細胞浸潤促進化 / 外側性骨造成 / 立体形状型骨補填材
Outline of Final Research Achievements

Various augmentation techniques can be used to provide sufficient bone volume for reliable placement of dental implants in the severely resorbed alveolar ridge. Autogenous bone grafting has been shown to provide predictable increases in bone volume for maxillary and mandibular alveolar augmentation.The benefits of autografts are restricted because of limited donor sources and associated morbidity. As a result, it would be desirable to use a readily available, safe, and effective substitute for autografts.
The Use of Porous Composite Uncalcined Hydroxyapatite / poly-DL-lacctide for Vertical Ridge Augmentation. We ascertained these combine blocks were appropriate the biodegrable and appropriate bone formation to been a useful material for vertical ridge augmentation.The purpose of this study was to assess the effect of vertical ridge augmentation using the HA/PDLLA block with Type 1・3 Collagen

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Annual Research Report
  • Research Products

    (3 results)

All 2016 2014

All Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] Effect of porous composite uncalcined hydroxyapatite / poly-DL-lacctide/type 1・3 collagen for vertical ridge augmentation.2016

    • Author(s)
      Akino N 、Tachikawa N、 Yukawa K、 Kasugai S
    • Organizer
      Acadamy of Osseointegration
    • Place of Presentation
      San Diego,USA
    • Year and Date
      2016-02-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 多孔性ハイドロキシアパタイト/ポリ-DL-乳酸/Ⅰ型・Ⅲ型コラーゲン複合体材料を用いた垂直的骨増生2016

    • Author(s)
      秋野 徳雄,立川 敬子,湯川 健,春日井 昇平
    • Organizer
      日本口腔インプラント学会
    • Place of Presentation
      京王プラザホテル、東京、新宿区
    • Year and Date
      2016-02-13
    • Related Report
      2015 Annual Research Report
  • [Presentation] β-リン酸三カルシウムブロックを用いた垂直的骨造成-Effect of beta-tricalcium phosphate block for vertical ridge augmentation.-2014

    • Author(s)
      秋野 徳雄,立川 敬子,春日井 昇平
    • Organizer
      日本顎顔面インプラント学会
    • Place of Presentation
      島根県・出雲市・ビックハート出雲
    • Year and Date
      2014-11-29
    • Related Report
      2014 Annual Research Report

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Published: 2014-09-09   Modified: 2017-05-10  

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