Research Project
Grant-in-Aid for Research Activity Start-up
In this study, the basic model of 3 dimensional intestinal tract and mucosa was reconstituted in vitro using several biological materials. The model was also examined by the oligonucleotide medicine or materials which had different molecular sizes. This basic model was important for the substitutional assay system of animal experimental models which predict drug absorption and pharmacokinetics and for the precise analysis where in vivo analysis could not achieve.
All 2016 2015 Other
All Journal Article (2 results) (of which Peer Reviewed: 1 results, Open Access: 2 results) Presentation (9 results) (of which Int'l Joint Research: 2 results, Invited: 1 results) Remarks (3 results)
Scientific Reports
Volume: 5 Issue: 1 Pages: 17035-17947
10.1038/srep17035
Drug Discoveries & Therapeutics
Volume: 9 Issue: 4 Pages: 303-309
10.5582/ddt.2015.01053
130005098743
http://www.osaka-ohtani.ac.jp/department/pharmacy/news/201512_3516.html
http://osakaohtani-yakuzai.wix.com/pharmaceutics
http://www3.osaka-ohtani.ac.jp/ph/3/index.htm