| Project/Area Number |
60570945
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| Research Category |
Grant-in-Aid for General Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Research Field |
外科・放射線系歯学
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| Research Institution | Showa University |
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Principal Investigator |
YOSHIDA Hiroshi (1987-1988) School of Dentistry, Showa University,Associate professor, 歯学部, 助教授 (80014330)
大野 康亮 (1985-1986) 昭和大, 歯学部, 助教授 (30112725)
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| Co-Investigator(Kenkyū-buntansha) |
OHTANI Shun-ichi School of Dentistry, Showa University,Assistant, 歯学部, 助手 (00176918)
ARISAWA Yasushi School of Dentistry, Showa University,Assistant, 歯学部, 助手 (80175984)
OHSAWA Takeaki School of Dentistry, Showa University,Assistant, 歯学部, 助手 (50146891)
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| Project Period (FY) |
1985 – 1987
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| Project Status |
Completed (Fiscal Year 1988)
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| Budget Amount *help |
¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 1987: ¥300,000 (Direct Cost: ¥300,000)
Fiscal Year 1986: ¥400,000 (Direct Cost: ¥400,000)
Fiscal Year 1985: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | Apatite-titanium Dental Implant / Maxillofacial Prosthesis / 顎顔面リハビリテーション / ハイドロキシアパタイト / 複合体人工歯根 / 顎補綴 / 術後顎欠損 / 言語障害 / アパタイト / 無歯顎 |
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| Research Abstract |
Maxillofacial prosthesis is useful for treatment of speech and mastication difficulties after surgery for oral cancer, but is often difficult in patients who have had extensive portions of the jaw removed with few or no remaining teeth. Retention and stabilization of a maxillofacial porsthesis in such patients are important. We made apatite-titanium dental implants to treat patients for whom it was difficult to retain and stalilize a maxillofacial prosthesis, and evaluated their usefulness both clinically and in experimental animals. Several kinds of experimental dental implants were made, among which were one-piece, two-piece, apatite alone and apatite-titaniumcomplex. Metal parts were of the OP-anchor type and cylindrical type, which allowed easier preparation. The following dental implants were used for this study : cylindrical, discoidal and sandwich. Various dental implants were implanted in the jaws of dogs. One to three months after implantation, the surface of the apatite root was directly bound to the newly formed woven bone and 7 and a half months to 1 year after implantation the apatite root was directly bound to the newly formed lamellar bone, which provided strong bone integration. Of the dental implants tested, the two-piece apatite-titanium roots seemed to be most useful. The dental implants used in clinically were based on the finding from the experimental studies. Two-piece apatite-titanium complex dental implants were used in patients in whom prostheses made by the conventional method could not be satisfactorily retained or stabillized after surgery for oral cancer. A maxillofacial prostheses with OP-anchor type attachment was worn by each patient. In all cases in which we applied our dental implants some improvement of stabilization of the prosthesis and of chewing efficiency was revealed. From these studies we conclude that clinical application of our dental implant system in maxillofacial rehabilitation would be possible and beneficial.
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